Protein: IVD
Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) (EC 1.3.8.1)

Gene: IVD
Organism: Homo sapiens
Interactions: 59
UniProt ID: P26440

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006552 - L-leucine catabolic process
GO:0008470 - 3-methylbutanoyl-CoA dehydrogenase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

686703

STK11
Serine/threonine-protein kinase STK11

2

2

High-throughput

0.628

High

568363

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

3

High-throughput

0.618

High

686693

IVD
Isovaleryl-CoA dehydrogenase, mitochondrial

1

15

High-throughput

0.618

High

686695

ETFB
Electron transfer flavoprotein subunit beta

1

3

High-throughput

0.618

High

686729

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

14

High-throughput

0.618

High

686711

NUD13
NAD(P)H pyrophosphatase NUDT13, mitochondrial

2

0

High-throughput

0.585

High

240803

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

686700

MPPA
Mitochondrial-processing peptidase subunit alpha

2

8

High-throughput

0.584

High

686696

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

2

2

High-throughput

0.574

High

686694

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

3

High-throughput

0.536

High

686712

ECHD2
Enoyl-CoA hydratase domain-containing protein 2, mitochondrial

1

9

High-throughput

0.536

High

686714

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

3

High-throughput

0.536

High

686723

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

1

High-throughput

0.536

High

686730

RT30
Large ribosomal subunit protein mL65

1

1

High-throughput

0.536

High

686731

LYRM2
LYR motif-containing protein 2

1

1

High-throughput

0.536

High

686733

DIC
Mitochondrial dicarboxylate carrier

1

3

High-throughput

0.536

High

686734

NPS3A
Protein NipSnap homolog 3A

1

2

High-throughput

0.536

High

460440

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

1

High-throughput

0.533

High

220474

RNF13
E3 ubiquitin-protein ligase RNF13

1

0

High-throughput

0.513

High

686707

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

686735

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

686722

TX101
Testis-expressed protein 101

1

2

High-throughput

0.489

High

279657

CISY
Citrate synthase, mitochondrial

1

6

High-throughput

0.479

High

281887

MPPB
Mitochondrial-processing peptidase subunit beta

1

8

High-throughput

0.479

High

350792

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

4

High-throughput

0.479

High

686697

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.479

High

686710

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

5

High-throughput

0.479

High

686715

S2541
Mitochondrial carrier protein SCaMC-3L

1

2

High-throughput

0.479

High

686717

MCUR1
Mitochondrial calcium uniporter regulator 1

1

4

High-throughput

0.479

High

686719

RRFM
Ribosome-recycling factor, mitochondrial

1

2

High-throughput

0.479

High

686721

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

2

High-throughput

0.479

High

686726

MTG2
Mitochondrial ribosome-associated GTPase 2

1

8

High-throughput

0.479

High

686728

MET17
Ribosome assembly protein METTL17, mitochondrial

1

4

High-throughput

0.479

High

686732

RMND1
Required for meiotic nuclear division protein 1 homolog

1

1

High-throughput

0.479

High

271310

ZBED4
Zinc finger BED domain-containing protein 4

1

0

High-throughput

0.458

High

686702

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.458

High

686725

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.458

High

653137

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

686724

S2532
Solute carrier family 25 member 32

1

3

High-throughput

0.445

High

686738

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

5

High-throughput

0.445

High

686716

PNMA1
Paraneoplastic antigen Ma1

1

1

High-throughput

0.439

High

686701

EEA1
Early endosome antigen 1

1

2

High-throughput

0.437

High

686709

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

686727

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

686705

CP135
Centrosomal protein of 135 kDa

1

2

High-throughput

0.407

High

686706

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.407

High

686698

ACTN3
Alpha-actinin-3

2

0

High-throughput

0.316

High

686737

GPSM3
G-protein-signaling modulator 3

2

0

High-throughput

0.316

High

608222

EGLN
Endoglin

1

0

High-throughput

0.279

Low

686708

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

686713

LRC49
Leucine-rich repeat-containing protein 49

1

0

High-throughput

0.279

Low

686718

TRI43
Tripartite motif-containing protein 43

1

0

High-throughput

0.279

Low

686736

WASC3
WASH complex subunit 3

1

0

High-throughput

0.279

Low

595686

H13
Histone H1.3

1

0

High-throughput

0.269

Low

686704

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

239437

PLIN1
Perilipin-1

1

0

High-throughput

0.249

Low

686699

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.249

Low

686720

MFSD3
Major facilitator superfamily domain-containing protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025