Protein: PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (hPar14) (Parvulin-17) (Par17) (hPar17) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Peptidyl-prolyl cis/trans isomerase EPVH) (hEPVH) (Rotamase Pin4)

Gene: PIN4
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q9Y237

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003681 - bent DNA binding
GO:0003690 - double-stranded DNA binding
GO:0003723 - RNA binding
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

848951

MAGAB
Melanoma-associated antigen 11

3

0

High-throughput

0.646

High

1385317

ZBTB9
Zinc finger and BTB domain-containing protein 9

2

5

High-throughput

0.628

High

364050

EGFR
Epidermal growth factor receptor

2

4

Small-scale

0.608

High

1317026

FAM9B
Protein FAM9B

2

0

High-throughput

0.601

High

1215982

MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

1

0

High-throughput

0.586

High

411122

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

4

High-throughput

0.576

High

1145797

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

4

High-throughput

0.576

High

1336506

PNMA1
Paraneoplastic antigen Ma1

1

1

High-throughput

0.573

High

998962

H31
Histone H3.1

2

0

High-throughput

0.559

High

348229

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

1

High-throughput

0.536

High

625711

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

1272080

SYPM
Probable proline--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1328537

RNF10
E3 ubiquitin-protein ligase RNF10

1

1

High-throughput

0.536

High

641708

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

4

High-throughput

0.526

High

1050726

DYN1
Dynamin-1

1

0

High-throughput

0.518

High

1155916

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.518

High

1431118

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.518

High

1095962

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.513

High

1286726

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.513

High

1430100

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.513

High

1462127

SYNRG
Synergin gamma

1

0

High-throughput

0.513

High

1490473

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.513

High

1330869

FRMD1
FERM domain-containing protein 1

1

3

High-throughput

0.512

High

644135

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

Small-scale

0.480

High

1015335

ERH
Enhancer of rudimentary homolog

1

0

Small-scale

0.479

High

260625

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

325169

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

401718

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

409138

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

965339

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.479

High

980561

H4
Histone H4

1

1

High-throughput

0.479

High

1027859

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.479

High

1194461

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

1225393

WAC2A
WASH complex subunit 2A

1

1

High-throughput

0.479

High

1229772

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

1350505

BICD2
Protein bicaudal D homolog 2

1

2

High-throughput

0.479

High

1459347

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

459809

PROF1
Profilin-1

1

0

High-throughput

0.458

High

485522

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

590059

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

696893

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

711681

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.458

High

769542

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

905301

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

1271914

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1372345

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.458

High

1421058

CE295
Centrosomal protein of 295 kDa

1

0

High-throughput

0.458

High

1452921

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.458

High

530607

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

1391080

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.445

High

1490474

WAC2C
WASH complex subunit 2C

1

1

High-throughput

0.445

High

539022

EPB41
Protein 4.1

1

1

High-throughput

0.437

High

887350

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

1454218

CEP72
Centrosomal protein of 72 kDa

2

0

High-throughput

0.327

High

1273212

CHSTF
Carbohydrate sulfotransferase 15

2

0

High-throughput

0.319

High

1379892

FATE1
Fetal and adult testis-expressed transcript protein

1

0

High-throughput

0.299

High

1117531

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

0

High-throughput

0.282

High

280373

SC22B
Vesicle-trafficking protein SEC22b

1

0

High-throughput

0.279

Low

482983

TPM1
Tropomyosin alpha-1 chain

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025