Protein: VWC2
Brorin (Brain-specific chordin-like protein) (von Willebrand factor C domain-containing protein 2)

Gene: VWC2
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q2TAL6

Gene Ontology (top 5):
GO:0005604 - basement membrane
GO:0005614 - interstitial matrix
GO:0005615 - extracellular space
GO:0010811 - positive regulation of cell-substrate adhesion
GO:0030514 - negative regulation of BMP signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1180127

ZN696
Zinc finger protein 696

3

6

High-throughput

0.607

High

1014856

HPCA
Neuron-specific calcium-binding protein hippocalcin

2

1

High-throughput

0.606

High

1180104

VASN
Vasorin

2

4

High-throughput

0.606

High

1180108

ATL4
ADAMTS-like protein 4

2

13

High-throughput

0.606

High

1180125

HPLN2
Hyaluronan and proteoglycan link protein 2

2

5

High-throughput

0.606

High

1180121

FUCO2
Plasma alpha-L-fucosidase

2

0

High-throughput

0.580

High

70225

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.553

High

221353

SPY1
Protein sprouty homolog 1

2

3

High-throughput

0.553

High

591932

F261
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

2

1

High-throughput

0.553

High

675526

TYY1
Transcriptional repressor protein YY1

2

10

High-throughput

0.553

High

685854

KRA59
Keratin-associated protein 5-9

2

20

High-throughput

0.553

High

733135

OTX1
Homeobox protein OTX1

2

7

High-throughput

0.553

High

789639

HPCL1
Hippocalcin-like protein 1

2

1

High-throughput

0.553

High

885255

HXA1
Homeobox protein Hox-A1

2

16

High-throughput

0.553

High

950492

KR108
Keratin-associated protein 10-8

2

19

High-throughput

0.553

High

1086953

PO4F2
POU domain, class 4, transcription factor 2

2

4

High-throughput

0.553

High

1180089

KR133
Keratin-associated protein 13-3

2

3

High-throughput

0.553

High

1180090

CRY2
Cryptochrome-2

2

1

High-throughput

0.553

High

1180091

KR132
Keratin-associated protein 13-2

2

3

High-throughput

0.553

High

1180092

LCE3E
Late cornified envelope protein 3E

2

3

High-throughput

0.553

High

1180094

LCE1C
Late cornified envelope protein 1C

2

2

High-throughput

0.553

High

1180095

LCE1F
Late cornified envelope protein 1F

2

1

High-throughput

0.553

High

1180096

LCE1A
Late cornified envelope protein 1A

2

1

High-throughput

0.553

High

1180097

LCE3A
Late cornified envelope protein 3A

2

1

High-throughput

0.553

High

1180099

LCE2C
Late cornified envelope protein 2C

2

1

High-throughput

0.553

High

1180100

LCE2D
Late cornified envelope protein 2D

2

1

High-throughput

0.553

High

1180103

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

8

High-throughput

0.553

High

1180106

ZN774
Zinc finger protein 774

2

2

High-throughput

0.553

High

1180109

ZN497
Zinc finger protein 497

2

1

High-throughput

0.553

High

1180110

F90A1
Protein FAM90A1

2

1

High-throughput

0.553

High

1180113

CTSR1
Cation channel sperm-associated protein 1

2

11

High-throughput

0.553

High

1180114

ZN417
Zinc finger protein 417

2

4

High-throughput

0.553

High

1180117

FBXW5
F-box/WD repeat-containing protein 5

2

1

High-throughput

0.553

High

1180118

ZN837
Zinc finger protein 837

2

2

High-throughput

0.553

High

1180119

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

2

High-throughput

0.553

High

1180120

ZN587
Zinc finger protein 587

2

4

High-throughput

0.553

High

1180123

LCE3D
Late cornified envelope protein 3D

2

3

High-throughput

0.553

High

1180126

ENKD1
Enkurin domain-containing protein 1

2

1

High-throughput

0.553

High

1180129

NTRI
Neurotrimin

2

4

High-throughput

0.553

High

1180130

ZN319
Zinc finger protein 319

2

1

High-throughput

0.553

High

1180131

UBQL2
Ubiquilin-2

2

3

High-throughput

0.553

High

1180132

ZN490
Zinc finger protein 490

2

10

High-throughput

0.553

High

1180133

UBQL1
Ubiquilin-1

2

3

High-throughput

0.553

High

380435

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

2

High-throughput

0.489

High

1180105

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

3

High-throughput

0.489

High

1180088

VWC2
Brorin

1

17

High-throughput

0.481

High

1180124

KRA24
Keratin-associated protein 2-4

1

18

High-throughput

0.470

High

505322

KRA23
Keratin-associated protein 2-3

1

18

High-throughput

0.439

High

1180101

LCE5A
Late cornified envelope protein 5A

1

2

High-throughput

0.439

High

1180102

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.437

High

224007

GET3
ATPase GET3

2

0

High-throughput

0.316

High

878663

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

2

0

High-throughput

0.316

High

1180093

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

1180098

LCE4A
Late cornified envelope protein 4A

2

0

High-throughput

0.316

High

1180107

ABH15
Protein ABHD15

2

0

High-throughput

0.316

High

1180111

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.316

High

1180112

CNNM3
Metal transporter CNNM3

2

0

High-throughput

0.316

High

1180115

TPC14
Trafficking protein particle complex subunit 14

2

0

High-throughput

0.316

High

1180116

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

0

High-throughput

0.316

High

1180122

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.316

High

1180128

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

2

0

High-throughput

0.316

High

1180134

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025