Protein: DHRS1
Dehydrogenase/reductase SDR family member 1 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 19C member 1) (Protein SDR19C1)

Gene: DHRS1
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q96LJ7

Gene Ontology (top 5):
GO:0004090 - carbonyl reductase (NADPH) activity
GO:0005783 - endoplasmic reticulum
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047045 - testosterone dehydrogenase (NADP+) activity
GO:0047881 - estradiol 17-alpha-dehydrogenase [NAD(P)+] activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

950628

KR108
Keratin-associated protein 10-8

3

10

High-throughput

0.616

High

1277359

NT2NA
Notch homolog 2 N-terminal-like protein A

2

2

High-throughput

0.578

High

948294

KR121
Keratin-associated protein 12-1

2

2

High-throughput

0.553

High

948373

KR122
Keratin-associated protein 12-2

2

11

High-throughput

0.553

High

949612

KR123
Keratin-associated protein 12-3

2

2

High-throughput

0.553

High

950865

KR109
Keratin-associated protein 10-9

2

11

High-throughput

0.553

High

1059719

KRA11
Keratin-associated protein 1-1

2

10

High-throughput

0.553

High

1092029

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

2

High-throughput

0.553

High

1205938

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

1

High-throughput

0.553

High

1235911

KRA51
Keratin-associated protein 5-1

2

1

High-throughput

0.553

High

1307437

KRA13
Keratin-associated protein 1-3

2

9

High-throughput

0.553

High

1379933

LHX4
LIM/homeobox protein Lhx4

2

1

High-throughput

0.553

High

1397068

KRA98
Keratin-associated protein 9-8

2

10

High-throughput

0.553

High

1397069

KR411
Keratin-associated protein 4-11

2

11

High-throughput

0.553

High

1397070

KRA41
Keratin-associated protein 4-1

2

10

High-throughput

0.553

High

685929

KRA59
Keratin-associated protein 5-9

1

12

High-throughput

0.523

High

1397066

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

895210

5HT6R
5-hydroxytryptamine receptor 6

1

1

High-throughput

0.494

High

733416

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.489

High

417684

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

280782

PR40A
Pre-mRNA-processing factor 40 homolog A

1

3

High-throughput

0.470

High

517084

NT2NC
Notch homolog 2 N-terminal-like protein C

1

2

High-throughput

0.470

High

949967

KR103
Keratin-associated protein 10-3

1

11

High-throughput

0.439

High

667990

CDK2
Cyclin-dependent kinase 2

1

2

High-throughput

0.437

High

965169

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.437

High

1163397

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.437

High

1397074

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

1397075

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.437

High

1397065

MDFI
MyoD family inhibitor

3

0

High-throughput

0.348

High

159084

LCE2B
Late cornified envelope protein 2B

2

0

High-throughput

0.316

High

300465

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.316

High

1186687

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

1257642

KRA52
Keratin-associated protein 5-2

2

0

High-throughput

0.316

High

1307054

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

1397072

DBLOH
Diablo IAP-binding mitochondrial protein

2

0

High-throughput

0.316

High

1397071

KRA32
Keratin-associated protein 3-2

1

0

High-throughput

0.299

High

180573

PLS1
Phospholipid scramblase 1

1

0

High-throughput

0.282

High

1397067

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.279

Low

1397073

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.279

Low

1397076

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

562322

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

1186792

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

1397077

SHLB1
Endophilin-B1

1

0

High-throughput

0.268

Low

602

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

377691

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1366522

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025