Protein: DUG1
Cys-Gly metallodipeptidase DUG1 (EC 3.4.13.-) (Deficient in utilization of glutathione protein 1) (GSH degradosomal complex subunit DUG1)

Gene: DUG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 36
UniProt ID: P43616

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006508 - proteolysis
GO:0006751 - glutathione catabolic process
GO:0008233 - peptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850672

DUG1
Cys-Gly metallodipeptidase DUG1

6

7

Small-scale

0.949

High

794307

DUG2
Probable di- and tripeptidase DUG2

1

7

Small-scale

0.713

High

579610

HSC82
ATP-dependent molecular chaperone HSC82

2

6

High-throughput

0.584

High

850681

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.479

High

367777

ENO1
Enolase 1

1

2

High-throughput

0.479

High

367996

ENO2
Enolase 2

1

2

High-throughput

0.479

High

392930

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

510597

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.479

High

709838

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

735038

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

802952

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.479

High

850061

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

850674

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

850675

DUG3
Probable glutamine amidotransferase DUG3

1

1

Small-scale

0.479

High

359030

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.458

High

368457

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

416453

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

439369

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

448549

RHO1
GTP-binding protein RHO1

1

0

High-throughput

0.458

High

555106

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

850678

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

850679

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

836287

BNI1
Protein BNI1

1

1

High-throughput

0.457

High

819080

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

850673

JJJ2
J protein JJJ2

1

2

High-throughput

0.445

High

670858

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

707441

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

850680

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

816715

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

536036

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

2

0

High-throughput

0.324

High

850676

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

0

High-throughput

0.269

Low

795058

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

826601

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

850677

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

792848

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025