Protein: 2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (Protein RTS1) (Protein SCS1)

Gene: 2A5D, RTS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 85
UniProt ID: P38903

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0000776 - kinetochore
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

660789

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

8

20

Small-scale

0.971

High

726145

2AAA
Protein phosphatase PP2A regulatory subunit A

6

20

Small-scale

0.943

High

660853

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

3

20

High-throughput

0.867

High

807001

SGO1
Shugoshin

6

0

Small-scale

0.699

High

806979

PPP5
Serine/threonine-protein phosphatase T

1

20

High-throughput

0.665

High

656312

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

6

Small-scale

0.647

High

743208

PP12
Serine/threonine-protein phosphatase PP1-2

1

11

Small-scale

0.618

High

359220

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

2

0

High-throughput

0.563

High

806969

SYEC
Glutamate--tRNA ligase, cytoplasmic

2

0

High-throughput

0.563

High

364523

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.561

High

807003

RIO1
Serine/threonine-protein kinase RIO1

2

0

High-throughput

0.547

High

741566

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.536

High

544845

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

806972

JSN1
Protein JSN1

1

0

High-throughput

0.518

High

806987

BOP3
Protein BOP3

1

0

High-throughput

0.518

High

779852

MID2
Cell wall integrity sensor MID2

1

3

High-throughput

0.494

High

806988

DNM1
Dynamin-related protein DNM1

1

0

High-throughput

0.493

High

806991

KIN4
Serine/threonine-protein kinase KIN4

1

3

Small-scale

0.481

High

806971

MAD3
Spindle assembly checkpoint component MAD3

1

5

Small-scale

0.479

High

806983

YG3A
Uncharacterized protein YGR130C

1

3

High-throughput

0.479

High

806989

2ABA
Protein phosphatase PP2A regulatory subunit B

1

1

High-throughput

0.479

High

806980

SLD3
DNA replication regulator SLD3

1

0

Small-scale

0.460

High

579371

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

679665

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

707071

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

747847

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

781928

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

806962

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

806966

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

806977

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

806992

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

Small-scale

0.458

High

806993

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.458

High

806994

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

807002

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

807004

PST2
Protoplast secreted protein 2

1

0

High-throughput

0.458

High

807006

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

1

0

Small-scale

0.458

High

531737

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

560698

KIN2
Serine/threonine-protein kinase KIN2

1

2

High-throughput

0.445

High

585932

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.445

High

622948

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.445

High

742847

HSP79
Heat shock protein homolog SSE2

1

2

High-throughput

0.445

High

743386

TOR2
Serine/threonine-protein kinase TOR2

1

2

High-throughput

0.445

High

806960

CSK2C
Casein kinase II subunit beta'

1

3

High-throughput

0.445

High

806963

BEM2
GTPase-activating protein BEM2/IPL2

1

1

High-throughput

0.445

High

806965

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

3

High-throughput

0.445

High

806968

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.445

High

806973

ASK10
Activator of SKN7 protein 10

1

3

High-throughput

0.445

High

806974

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

806975

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.445

High

806976

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.445

High

806986

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

1

3

High-throughput

0.445

High

806996

RGC1
Regulator of the glycerol channel 1

1

3

High-throughput

0.445

High

806981

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.438

High

755094

GCN1
eIF-2-alpha kinase activator GCN1

1

16

High-throughput

0.437

High

394550

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

427274

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.426

High

432578

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.426

High

435086

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.426

High

510479

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

526672

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

675994

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

758210

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.426

High

806978

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.426

High

806982

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.426

High

806995

AVO2
Target of rapamycin complex 2 subunit AVO2

1

0

High-throughput

0.426

High

806997

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

High-throughput

0.426

High

806998

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.426

High

807000

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.426

High

441904

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.407

High

806961

RS14B
Small ribosomal subunit protein uS11B

1

1

High-throughput

0.407

High

482014

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.279

Low

806970

SSY5
SPS-sensor serine protease component SSY5

1

0

Small-scale

0.251

Low

806967

PTR3
SPS-sensor component PTR3

1

0

High-throughput

0.249

Low

798092

OM14
Mitochondrial outer membrane protein OM14

1

0

High-throughput

0.238

Low

456524

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

0

High-throughput

0.232

Low

626730

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

642139

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.232

Low

689451

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.232

Low

712567

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.232

Low

806964

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.232

Low

806984

PXR1
Protein PXR1

1

0

High-throughput

0.232

Low

806985

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.232

Low

806990

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.232

Low

806999

BFR2
Protein BFR2

1

0

High-throughput

0.232

Low

807005

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025