Protein: RTF1
RNA polymerase-associated protein RTF1

Gene: RTF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: P53064

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000791 - euchromatin
GO:0001015 - snoRNA transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

916879

CTR9
RNA polymerase-associated protein CTR9

15

2

Small-scale

0.762

High

798604

PAF1
RNA polymerase II-associated protein 1

14

2

Small-scale

0.761

High

916887

CDC73
Cell division control protein 73

14

1

Small-scale

0.761

High

800258

LEO1
RNA polymerase-associated protein LEO1

11

2

Small-scale

0.758

High

739697

SPT16
FACT complex subunit SPT16

9

0

Small-scale

0.717

High

916883

POB3
FACT complex subunit POB3

5

1

Small-scale

0.709

High

694596

SPT5
Transcription elongation factor SPT5

3

2

Small-scale

0.688

High

585981

CSK21
Casein kinase II subunit alpha

3

5

Small-scale

0.667

High

744322

CHD1
Chromo domain-containing protein 1

3

0

Small-scale

0.648

High

438542

UBC2
Ubiquitin-conjugating enzyme E2 2

3

2

Small-scale

0.646

High

402058

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

1

Small-scale

0.646

High

916873

RTF1
RNA polymerase-associated protein RTF1

1

0

High-throughput

0.631

High

364649

CDK1
Cyclin-dependent kinase 1

2

2

Small-scale

0.584

High

594474

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.569

High

750977

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

Small-scale

0.561

High

633262

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

Small-scale

0.537

High

793438

ATR
Serine/threonine-protein kinase MEC1

1

0

Small-scale

0.537

High

762992

SPT7
SAGA complex subunit SPT7

1

2

High-throughput

0.536

High

916880

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

Small-scale

0.529

High

751434

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.493

High

916893

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

916888

SWC7
SWR1-complex protein 7

1

0

High-throughput

0.486

High

470561

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.480

High

381171

H2B1
Histone H2B.1

1

2

Small-scale

0.479

High

419462

H2A1
Histone H2A.1

1

1

Small-scale

0.479

High

779290

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.479

High

823188

RAD26
DNA repair and recombination protein RAD26

1

1

Small-scale

0.479

High

916881

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

749700

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

436465

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

645189

PSB4
Proteasome subunit beta type-4

1

0

Small-scale

0.458

High

661180

SPT6
Transcription elongation factor SPT6

1

0

High-throughput

0.458

High

670934

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

677485

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

679884

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

707664

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

709877

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

735070

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

748302

SPT4
Transcription elongation factor SPT4

1

0

High-throughput

0.458

High

792147

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

805557

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

Small-scale

0.458

High

826034

ULP2
Ubiquitin-like-specific protease 2

1

0

Small-scale

0.458

High

826665

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

865676

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

874247

CLA4
Serine/threonine-protein kinase CLA4

1

0

Small-scale

0.458

High

916874

INO80
Chromatin-remodeling ATPase INO80

1

0

Small-scale

0.458

High

916875

ELOA1
Elongin-A

1

0

Small-scale

0.458

High

916877

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

916882

LCD1
DNA damage checkpoint protein LCD1

1

0

Small-scale

0.458

High

916885

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

916886

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

Small-scale

0.458

High

916890

SGO1
Shugoshin

1

0

High-throughput

0.458

High

916891

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

916892

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

916894

SKS1
Serine/threonine-protein kinase SKS1

1

0

High-throughput

0.458

High

444573

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.445

High

527200

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

545592

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

727185

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

579751

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.437

High

916876

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

752514

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

803492

TDA3
Putative oxidoreductase TDA3

1

0

High-throughput

0.279

Low

916884

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low

796338

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

858511

STB2
Protein STB2

1

0

High-throughput

0.251

Low

448900

TYSY
Thymidylate synthase

1

0

Small-scale

0.249

Low

844539

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

864782

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

877859

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

916889

CRT10
Protein CRT10

1

0

Small-scale

0.249

Low

394737

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

810854

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

893130

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

0

High-throughput

0.232

Low

916878

ZDS2
Protein ZDS2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025