Protein: YTM1
Ribosome biogenesis protein YTM1 (Microtubule-associated protein YTM1)

Gene: YTM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 162
UniProt ID: Q12024

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919038

PESC
Pescadillo homolog

20

4

Small-scale

0.987

High

1047302

ERB1
Ribosome biogenesis protein ERB1

13

20

Small-scale

0.985

High

682416

SPB4
ATP-dependent rRNA helicase SPB4

6

20

High-throughput

0.937

High

1043310

HAS1
ATP-dependent RNA helicase HAS1

6

20

Small-scale

0.937

High

1084130

DBP10
ATP-dependent RNA helicase DBP10

6

20

High-throughput

0.937

High

793545

MAK5
ATP-dependent RNA helicase MAK5

5

20

High-throughput

0.919

High

746690

DRS1
ATP-dependent RNA helicase DRS1

5

20

Small-scale

0.915

High

677258

SPB1
27S pre-rRNA

3

10

High-throughput

0.827

High

633204

MAK11
Protein MAK11

3

18

Small-scale

0.817

High

1084123

YTM1
Ribosome biogenesis protein YTM1

2

16

Small-scale

0.754

High

782481

RPF2
Ribosome biogenesis protein RPF2

10

2

Small-scale

0.752

High

917582

NSA1
Ribosome biogenesis protein NSA1

10

3

Small-scale

0.752

High

803964

CIC1
Proteasome-interacting protein CIC1

8

6

Small-scale

0.746

High

830208

NOP2
25S rRNA

7

8

Small-scale

0.742

High

804685

SSF1
Ribosome biogenesis protein SSF1

7

3

Small-scale

0.740

High

814414

NOC2
Nucleolar complex protein 2

7

1

Small-scale

0.740

High

1039654

NOG1
Nucleolar GTP-binding protein 1

7

7

Small-scale

0.736

High

1084127

MAK21
Ribosome biogenesis protein MAK21

6

7

High-throughput

0.729

High

827635

RLP7
Ribosome biogenesis protein RLP7

6

9

Small-scale

0.726

High

924866

NOP15
Ribosome biogenesis protein 15

5

20

High-throughput

0.712

High

1060747

NOC3
Nucleolar complex-associated protein 3

5

3

Small-scale

0.709

High

1046534

PUF6
Pumilio homology domain family member 6

5

4

Small-scale

0.706

High

712689

RL8B
Large ribosomal subunit protein eL8B

2

11

High-throughput

0.705

High

1084132

IF6
Eukaryotic translation initiation factor 6

4

2

Small-scale

0.694

High

1030603

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

14

High-throughput

0.691

High

805110

RPF1
Ribosome production factor 1

4

1

High-throughput

0.691

High

816929

NUG1
Nuclear GTP-binding protein NUG1

4

11

High-throughput

0.686

High

818294

NSA2
Ribosome biogenesis protein NSA2

4

3

Small-scale

0.676

High

780341

EBP2
rRNA-processing protein EBP2

4

3

Small-scale

0.672

High

1084112

MDN1
Midasin

3

19

Small-scale

0.665

High

791130

NOP4
Nucleolar protein 4

3

15

High-throughput

0.662

High

763136

RRP1
Ribosomal RNA-processing protein 1

3

6

Small-scale

0.656

High

1050201

RRP5
rRNA biogenesis protein RRP5

3

20

High-throughput

0.656

High

1062789

BRX1
Ribosome biogenesis protein BRX1

3

11

Small-scale

0.656

High

1065568

NIP7
60S ribosome subunit biogenesis protein NIP7

3

1

Small-scale

0.656

High

948687

ACT
Actin

1

9

High-throughput

0.646

High

1044914

RRP17
Ribosomal RNA-processing protein 17

3

1

High-throughput

0.640

High

865431

URB2
Nucleolar pre-ribosomal-associated protein 2

3

0

High-throughput

0.618

High

382403

H4
Histone H4

1

9

High-throughput

0.618

High

419902

H2A2
Histone H2A.2

1

10

High-throughput

0.618

High

637299

PWP1
Periodic tryptophan protein 1

1

16

High-throughput

0.618

High

751506

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

8

High-throughput

0.618

High

781666

DBP7
ATP-dependent RNA helicase DBP7

1

20

High-throughput

0.618

High

792297

GBLP
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.618

High

864547

MTR4
ATP-dependent RNA helicase DOB1

1

20

Small-scale

0.618

High

963779

H3
Histone H3

1

11

High-throughput

0.618

High

1046080

DHR1
Probable ATP-dependent RNA helicase DHR1

1

18

High-throughput

0.618

High

1046129

RRB1
Ribosome assembly protein RRB1

1

19

High-throughput

0.618

High

1054411

DBP9
ATP-dependent RNA helicase DBP9

1

20

High-throughput

0.618

High

816811

NOP16
Nucleolar protein 16

3

0

Small-scale

0.613

High

531921

RL4A
Large ribosomal subunit protein uL4A

2

5

High-throughput

0.611

High

750169

MRT4
Ribosome assembly factor MRT4

2

12

High-throughput

0.611

High

918207

NMA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

0

High-throughput

0.586

High

850035

LOC1
60S ribosomal subunit assembly/export protein LOC1

2

0

High-throughput

0.585

High

570178

RL3
Large ribosomal subunit protein uL3

2

9

High-throughput

0.584

High

798347

ENP1
Essential nuclear protein 1

2

2

High-throughput

0.584

High

844655

UTP10
U3 small nucleolar RNA-associated protein 10

2

4

High-throughput

0.584

High

1054265

FKBP4
FK506-binding protein 4

2

9

High-throughput

0.584

High

1060432

GRC3
Polynucleotide 5'-hydroxyl-kinase GRC3

2

1

High-throughput

0.584

High

1060834

RLP24
Ribosome biogenesis protein RLP24

2

4

Small-scale

0.584

High

1084124

NOP53
Ribosome biogenesis protein NOP53

2

3

High-throughput

0.584

High

1084131

NOP58
Nucleolar protein 58

2

8

High-throughput

0.584

High

671221

SIS1
Protein SIS1

2

13

High-throughput

0.571

High

1064856

RRS1
Regulator of ribosome biosynthesis

2

3

High-throughput

0.571

High

1084126

SSF2
Ribosome biogenesis protein SSF2

2

3

High-throughput

0.571

High

383936

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.553

High

601152

RL8A
Large ribosomal subunit protein eL8A

1

11

Small-scale

0.553

High

874578

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.553

High

527945

HSP72
Heat shock protein SSA2

2

18

High-throughput

0.552

High

546636

SSB1
Ribosome-associated molecular chaperone SSB1

2

18

High-throughput

0.552

High

820050

SSB2
Ribosome-associated molecular chaperone SSB2

2

18

High-throughput

0.552

High

432724

RL7A
Large ribosomal subunit protein uL30A

1

9

High-throughput

0.536

High

684876

RL5
Large ribosomal subunit protein uL18

1

6

High-throughput

0.536

High

722335

XPO1
Exportin-1

1

12

High-throughput

0.536

High

743309

PP12
Serine/threonine-protein phosphatase PP1-2

1

9

High-throughput

0.536

High

1060418

RIX7
Ribosome biogenesis ATPase RIX7

1

12

High-throughput

0.536

High

1063913

DNLI4
DNA ligase 4

1

1

High-throughput

0.536

High

1084128

RL7B
Large ribosomal subunit protein uL30B

1

9

High-throughput

0.536

High

671736

SCJ1
DnaJ-related protein SCJ1

2

11

High-throughput

0.533

High

811190

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.514

High

865103

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.514

High

448236

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.513

High

798192

YB92
5'-deoxynucleotidase YBR242W

1

0

High-throughput

0.513

High

924035

ELOA1
Elongin-A

1

0

High-throughput

0.513

High

1059617

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

1060024

YPD1
Phosphorelay intermediate protein YPD1

1

0

High-throughput

0.513

High

440869

KIN28
Serine/threonine-protein kinase KIN28

1

11

High-throughput

0.501

High

632013

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.489

High

757394

VPS35
Vacuolar protein sorting-associated protein 35

1

1

High-throughput

0.489

High

808565

TEM1
Protein TEM1

1

6

High-throughput

0.489

High

824954

TM108
Protein TMA108

1

2

High-throughput

0.489

High

1084125

RTK1
Probable serine/threonine-protein kinase RTK1

1

8

High-throughput

0.489

High

1084133

RL13A
Large ribosomal subunit protein eL13A

1

4

High-throughput

0.489

High

149997

RS9A
Small ribosomal subunit protein uS4A

1

6

High-throughput

0.479

High

410384

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.479

High

433892

RL26A
Large ribosomal subunit protein uL24A

1

4

High-throughput

0.479

High

435422

RS3
Small ribosomal subunit protein uS3

1

6

High-throughput

0.479

High

442158

RS14A
Small ribosomal subunit protein uS11A

1

5

High-throughput

0.479

High

449023

TOP2
DNA topoisomerase 2

1

10

High-throughput

0.479

High

512705

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.479

High

515340

RL35A
Large ribosomal subunit protein uL29A

1

2

Small-scale

0.479

High

534161

MAK16
Protein MAK16

1

3

High-throughput

0.479

High

646560

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

674884

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.479

High

677606

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.479

High

689159

RL16A
Large ribosomal subunit protein uL13A

1

7

High-throughput

0.479

High

689711

RS7A
Small ribosomal subunit protein eS7A

1

4

High-throughput

0.479

High

708460

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

795858

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

806675

RIX1
Pre-rRNA-processing protein RIX1

1

1

Small-scale

0.479

High

807172

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

11

High-throughput

0.479

High

823056

ATAD2
ATPase histone chaperone YTA7

1

14

High-throughput

0.479

High

826106

ULP2
Ubiquitin-like-specific protease 2

1

7

High-throughput

0.479

High

919782

YG5X
Putative methyltransferase YGR283C

1

1

High-throughput

0.479

High

923223

NOG2
Nucleolar GTP-binding protein 2

1

11

High-throughput

0.479

High

924347

NOP13
Nucleolar protein 13

1

20

High-throughput

0.479

High

925119

APJ1
J domain-containing protein APJ1

1

14

High-throughput

0.479

High

925455

RCM1
25S rRNA

1

8

High-throughput

0.479

High

1042261

TOM1
E3 ubiquitin-protein ligase TOM1

1

8

High-throughput

0.479

High

1046820

UTP14
U3 small nucleolar RNA-associated protein 14

1

12

High-throughput

0.479

High

1049094

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.479

High

1053999

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

1054375

JIP5
WD repeat-containing protein JIP5

1

18

High-throughput

0.479

High

1055514

NOC4
Nucleolar complex protein 4

1

7

High-throughput

0.479

High

1062348

NOP12
Nucleolar protein 12

1

18

High-throughput

0.479

High

677981

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

735215

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

780722

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

826914

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

1055482

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

1064278

SGO1
Shugoshin

1

0

High-throughput

0.458

High

405152

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.457

High

525456

HSP71
Heat shock protein SSA1

1

16

High-throughput

0.445

High

742616

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

455306

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

503291

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

504461

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

513273

RS8A
Small ribosomal subunit protein eS8A

1

4

High-throughput

0.437

High

514877

RS18A
Small ribosomal subunit protein uS13A

1

3

High-throughput

0.437

High

680625

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

5

High-throughput

0.437

High

747624

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

753640

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

778579

RS27A
Small ribosomal subunit protein eS27A

1

3

High-throughput

0.437

High

802435

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.437

High

812744

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

909773

YPT32
GTP-binding protein YPT32/YPT11

1

3

High-throughput

0.437

High

918489

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.437

High

1025060

NUM1
Nuclear migration protein NUM1

1

11

High-throughput

0.437

High

1033618

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

1046325

VMS1
tRNA endonuclease VMS1

1

2

High-throughput

0.437

High

1064749

HRK1
Serine/threonine-protein kinase HRK1

1

7

High-throughput

0.437

High

1064816

RS10A
Small ribosomal subunit protein eS10A

1

7

High-throughput

0.437

High

386901

TBB
Tubulin beta chain

1

17

High-throughput

0.407

High

394989

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.407

High

427475

RLA0
Large ribosomal subunit protein uL10

1

12

High-throughput

0.407

High

453840

PYR1
Multifunctional protein URA2

1

9

High-throughput

0.407

High

1084129

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

1048245

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low

558895

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

1059399

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

863776

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025