Protein: CLPX
ATP-dependent clpX-like chaperone, mitochondrial (mtClpX) (ATP-dependent unfoldase ClpX)

Gene: CLPX, MCX1
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: P38323

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0016887 - ATP hydrolysis activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704780

MSP1
Outer mitochondrial transmembrane helix translocase

1

19

Small-scale

0.618

High

752194

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.618

High

488658

HEM1
5-aminolevulinate synthase, mitochondrial

1

1

Small-scale

0.561

High

763316

TAF14
Transcription initiation factor TFIID subunit 14

1

1

High-throughput

0.494

High

575333

EI2BA
Translation initiation factor eIF2B subunit alpha

1

1

High-throughput

0.489

High

798051

TEM1
Protein TEM1

1

5

High-throughput

0.489

High

510440

HSP77
Import motor subunit, mitochondrial

1

12

High-throughput

0.479

High

780489

MCR1
NADH-cytochrome b5 reductase 2

1

8

Small-scale

0.479

High

798065

NUM1
Nuclear migration protein NUM1

1

9

High-throughput

0.479

High

798067

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.479

High

798079

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

798081

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.479

High

382895

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

638908

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.458

High

783853

RM04
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.458

High

392646

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.457

High

359208

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

4

High-throughput

0.445

High

365608

PGK
Phosphoglycerate kinase

1

3

High-throughput

0.445

High

367743

ENO1
Enolase 1

1

3

High-throughput

0.445

High

367954

ENO2
Enolase 2

1

3

High-throughput

0.445

High

394505

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.445

High

444500

DED1
ATP-dependent RNA helicase DED1

1

2

High-throughput

0.445

High

523777

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

544681

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

554690

YPK1
Serine/threonine-protein kinase YPK1

1

7

High-throughput

0.445

High

597446

EF3A
Elongation factor 3A

1

3

High-throughput

0.445

High

599006

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

3

High-throughput

0.445

High

632662

DBP4
ATP-dependent RNA helicase HCA4

1

8

High-throughput

0.445

High

645728

HSP74
Heat shock protein SSA4

1

7

High-throughput

0.445

High

775945

LRG1
Rho-GTPase-activating protein LRG1

1

7

High-throughput

0.445

High

798052

HSP7E
Heat shock protein SSC3, mitochondrial

1

13

High-throughput

0.445

High

798071

SYRC
Arginine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.445

High

149727

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.437

High

435048

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.437

High

435926

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

455028

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

512407

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

512974

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

670633

SIS1
Protein SIS1

1

5

High-throughput

0.437

High

674587

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.437

High

798063

HST2
NAD-dependent protein deacetylase HST2

1

5

High-throughput

0.437

High

452571

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.426

High

572568

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.426

High

798061

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.426

High

381087

H2B1
Histone H2B.1

1

6

High-throughput

0.407

High

434553

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.407

High

645817

VATE
V-type proton ATPase subunit E

1

1

High-throughput

0.407

High

757371

VPS35
Vacuolar protein sorting-associated protein 35

1

1

High-throughput

0.407

High

796562

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

8

High-throughput

0.407

High

798053

NUG1
Nuclear GTP-binding protein NUG1

1

2

High-throughput

0.407

High

798055

EPS1
ER-retained PMA1-suppressing protein 1

1

10

High-throughput

0.407

High

798058

ARC1
tRNA-aminoacylation cofactor ARC1

1

3

High-throughput

0.407

High

798069

RRP5
rRNA biogenesis protein RRP5

1

6

High-throughput

0.407

High

798075

UTP4
U3 small nucleolar RNA-associated protein 4

1

15

High-throughput

0.407

High

798076

ELP1
Elongator complex protein 1

1

1

High-throughput

0.407

High

798077

SHS1
Seventh homolog of septin 1

1

6

High-throughput

0.407

High

798080

RPN6
26S proteasome regulatory subunit RPN6

1

17

High-throughput

0.407

High

64244

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

706946

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

798060

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

798068

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

798073

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

638798

REB1
DNA-binding protein REB1

1

0

High-throughput

0.232

Low

736640

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low

738584

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.232

Low

798050

RGD3
Rho-GTPase-activating protein RGD3

1

0

High-throughput

0.232

Low

798054

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.232

Low

798056

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.232

Low

798057

KRI1
Protein KRI1

1

0

High-throughput

0.232

Low

798059

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.232

Low

798062

PESC
Pescadillo homolog

1

0

High-throughput

0.232

Low

798064

YN87
Uncharacterized protein YNR014W

1

0

High-throughput

0.232

Low

798066

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.232

Low

798070

BCH1
Protein BCH1

1

0

High-throughput

0.232

Low

798072

DUS3
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]

1

0

High-throughput

0.232

Low

798074

ARO10
Transaminated amino acid decarboxylase

1

0

High-throughput

0.232

Low

798078

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.232

Low

798082

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025