Protein: NUP2
Nucleoporin NUP2 (Nuclear pore protein NUP2) (p95)

Gene: NUP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 101
UniProt ID: P32499

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0000972 - transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

738503

IMA1
Importin subunit alpha

17

20

Small-scale

0.988

High

738457

GSP1
GTP-binding nuclear protein GSP1/CNR1

3

20

Small-scale

0.829

High

738510

IMB1
Importin subunit beta-1

14

20

Small-scale

0.761

High

738472

NUP60
Nucleoporin NUP60

12

2

Small-scale

0.759

High

738473

IMB4
Importin subunit beta-4

4

20

Small-scale

0.686

High

737800

HOG1
Mitogen-activated protein kinase HOG1

3

9

Small-scale

0.664

High

738484

NUP57
Nucleoporin NUP57

3

20

High-throughput

0.658

High

544185

SSB1
Ribosome-associated molecular chaperone SSB1

3

13

High-throughput

0.650

High

738452

NUP2
Nucleoporin NUP2

1

19

Small-scale

0.647

High

634213

NUP1
Nucleoporin NUP1

3

18

Small-scale

0.640

High

738500

NU100
Nucleoporin NUP100/NSP100

3

20

Small-scale

0.640

High

641419

RCC1
Guanine nucleotide exchange factor SRM1

2

13

Small-scale

0.624

High

577277

NSP1
Nucleoporin NSP1

2

20

High-throughput

0.614

High

738498

NUP49
Nucleoporin NUP49/NSP49

2

20

High-throughput

0.614

High

646346

RAD53
Serine/threonine-protein kinase RAD53

2

2

Small-scale

0.595

High

738464

NU170
Nucleoporin NUP170

2

12

Small-scale

0.595

High

738480

NUP85
Nucleoporin NUP85

2

3

Small-scale

0.595

High

738453

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

3

Small-scale

0.584

High

738477

MLP2
Protein MLP2

2

15

High-throughput

0.584

High

738491

NUP84
Nucleoporin NUP84

2

9

High-throughput

0.584

High

738499

MLP1
Protein MLP1

2

19

High-throughput

0.584

High

523375

HSP71
Heat shock protein SSA1

2

13

High-throughput

0.571

High

579051

HSC82
ATP-dependent molecular chaperone HSC82

2

6

High-throughput

0.571

High

738501

NU116
Nucleoporin NUP116/NSP116

2

20

Small-scale

0.571

High

738459

XPOT
Exportin-T

1

20

Small-scale

0.552

High

526190

HSP72
Heat shock protein SSA2

2

13

High-throughput

0.552

High

738515

SMT3
Ubiquitin-like protein SMT3

2

11

High-throughput

0.548

High

738460

NIC96
Nucleoporin NIC96

1

6

High-throughput

0.541

High

738482

NU192
Nucleoporin NUP192

1

7

High-throughput

0.541

High

738492

MSN5
Protein MSN5

1

20

Small-scale

0.527

High

738455

KA122
Importin beta-like protein KAP122

1

2

Small-scale

0.515

High

531279

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.513

High

738468

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.508

High

734636

IMB3
Importin subunit beta-3

1

20

Small-scale

0.501

High

738506

ARX1
Probable metalloprotease ARX1

1

2

Small-scale

0.501

High

738463

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

7

High-throughput

0.489

High

738488

UBC9
SUMO-conjugating enzyme UBC9

1

5

Small-scale

0.481

High

738514

SIZ2
E3 SUMO-protein ligase SIZ2

1

3

Small-scale

0.481

High

392425

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

403411

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

2

High-throughput

0.479

High

734887

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

738462

NU133
Nucleoporin NUP133

1

7

High-throughput

0.479

High

738465

ATG8
Autophagy-related protein 8

1

4

Small-scale

0.479

High

738466

BRL1
Nucleus export protein BRL1

1

1

Small-scale

0.479

High

738476

NUP82
Nucleoporin NUP82

1

2

High-throughput

0.479

High

738478

NU159
Nucleoporin NUP159

1

20

High-throughput

0.479

High

738481

NMD5
Nonsense-mediated mRNA decay protein 5

1

20

Small-scale

0.479

High

738483

MOG1
Nuclear import protein MOG1

1

2

High-throughput

0.479

High

738485

NUP42
Nucleoporin NUP42

1

20

High-throughput

0.479

High

738486

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

8

High-throughput

0.479

High

738490

NU188
Nucleoporin NUP188

1

2

High-throughput

0.479

High

738495

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

738502

ULP1
Ubiquitin-like-specific protease 1

1

7

High-throughput

0.479

High

738505

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

738513

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

738519

LAS17
Proline-rich protein LAS17

1

4

Small-scale

0.479

High

738521

MEX67
mRNA export factor MEX67

1

14

High-throughput

0.479

High

738511

RHC31
DNA damage tolerance protein RHC31

1

0

Small-scale

0.460

High

438132

NOT2
General negative regulator of transcription subunit 2

1

0

Small-scale

0.458

High

736617

ASF1
Histone chaperone ASF1

1

0

Small-scale

0.458

High

738517

NDJ1
Non-disjunction protein 1

1

0

Small-scale

0.458

High

358155

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.445

High

366974

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.445

High

386632

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

394357

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

481536

HSP73
Heat shock protein SSA3

1

13

High-throughput

0.445

High

486431

TBA3
Tubulin alpha-3 chain

1

2

High-throughput

0.445

High

510310

HSP77
Import motor subunit, mitochondrial

1

9

High-throughput

0.445

High

592102

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

597078

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.445

High

738454

HSP7F
Heat shock protein homolog SSE1

1

17

High-throughput

0.445

High

738458

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

738467

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

738474

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

738475

JEM1
DnaJ-like chaperone JEM1

1

4

High-throughput

0.445

High

738516

HSP42
Heat shock protein 42

1

2

High-throughput

0.445

High

738509

SIZ1
E3 SUMO-protein ligase SIZ1

1

4

Small-scale

0.439

High

594256

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

645894

DBF2
Cell cycle protein kinase DBF2

1

7

High-throughput

0.437

High

670475

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

706520

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

738461

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

Small-scale

0.437

High

738470

TCPZ
T-complex protein 1 subunit zeta

1

2

High-throughput

0.437

High

738479

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

738496

ACT
Actin

1

3

Small-scale

0.437

High

738504

HOT1
High-osmolarity-induced transcription protein 1

1

2

Small-scale

0.437

High

738507

RUVB1
RuvB-like protein 1

1

1

Small-scale

0.437

High

738512

AP3D
AP-3 complex subunit delta

1

5

High-throughput

0.437

High

738518

DBP10
ATP-dependent RNA helicase DBP10

1

3

High-throughput

0.437

High

738520

RUVB2
RuvB-like protein 2

1

1

Small-scale

0.437

High

364982

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

738456

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

0

High-throughput

0.426

High

738497

UBC7
Ubiquitin-conjugating enzyme E2 7

1

7

High-throughput

0.417

High

738471

CAJ1
Protein CAJ1

1

3

High-throughput

0.407

High

738487

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

5

High-throughput

0.407

High

738489

SPT20
SAGA complex subunit SPT20

1

1

High-throughput

0.407

High

738493

POP3
Ribonucleases P/MRP protein subunit POP3

1

0

High-throughput

0.279

Low

738469

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

738494

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.249

Low

738508

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025