Protein: VMS1
tRNA endonuclease VMS1 (EC 3.1.-.-) (VCP/CDC48-associated mitochondrial stress-responsive protein 1)

Gene: VMS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 238
UniProt ID: Q04311

Gene Ontology (top 5):
GO:0004045 - peptidyl-tRNA hydrolase activity
GO:0004521 - RNA endonuclease activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

680039

CDC48
Cell division control protein 48

12

5

Small-scale

0.759

High

1046293

VMS1
tRNA endonuclease VMS1

1

3

Small-scale

0.713

High

932798

UFD2
E4 ubiquitin-protein ligase UFD2

3

0

Small-scale

0.628

High

817288

ARB1
ABC transporter ATP-binding protein ARB1

2

2

Small-scale

0.584

High

754449

NPL4
Nuclear protein localization protein 4

2

0

Small-scale

0.576

High

1046333

IF6
Eukaryotic translation initiation factor 6

2

3

Small-scale

0.571

High

1046145

UBX2
UBX domain-containing protein 2

2

0

Small-scale

0.559

High

1046334

RQC2
Ribosome quality control complex subunit 2

2

0

Small-scale

0.559

High

757904

UBX1
UBX domain-containing protein 1

1

0

Small-scale

0.513

High

453998

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.493

High

154226

RL36B
Large ribosomal subunit protein eL36B

1

1

High-throughput

0.479

High

383192

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.479

High

409782

RL24A
Large ribosomal subunit protein eL24A

1

6

High-throughput

0.479

High

410329

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

427436

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.479

High

432695

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.479

High

432915

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.479

High

433077

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.479

High

434085

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.479

High

434193

RL36A
Large ribosomal subunit protein eL36A

1

1

High-throughput

0.479

High

434648

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

438770

SC160
Protein SCP160

1

2

High-throughput

0.479

High

452599

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

High-throughput

0.479

High

482089

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.479

High

502752

RS21A
Small ribosomal subunit protein eS21A

1

1

High-throughput

0.479

High

504405

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.479

High

504556

RL31B
Large ribosomal subunit protein eL31B

1

3

High-throughput

0.479

High

511286

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.479

High

511486

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.479

High

513408

RL23B
Large ribosomal subunit protein uL14B

1

1

High-throughput

0.479

High

513572

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

513769

RL2A
Large ribosomal subunit protein uL2A

1

1

High-throughput

0.479

High

514189

RS16B
Small ribosomal subunit protein uS9B

1

1

High-throughput

0.479

High

515170

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.479

High

531881

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.479

High

570137

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

577211

SEC63
Protein translocation protein SEC63

1

2

High-throughput

0.479

High

632289

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.479

High

637278

PWP1
Periodic tryptophan protein 1

1

2

High-throughput

0.479

High

641447

RCC1
Guanine nucleotide exchange factor SRM1

1

1

High-throughput

0.479

High

663722

RL24B
Large ribosomal subunit protein eL24B

1

6

High-throughput

0.479

High

666543

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.479

High

674827

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

676770

GBP2
Serine/arginine

1

1

High-throughput

0.479

High

678453

PWP2
Periodic tryptophan protein 2

1

1

High-throughput

0.479

High

684837

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

689131

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

689281

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

708108

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

712665

RL8B
Large ribosomal subunit protein eL8B

1

2

High-throughput

0.479

High

750143

MRT4
Ribosome assembly factor MRT4

1

1

High-throughput

0.479

High

779966

DOA1
Protein DOA1

1

3

Small-scale

0.479

High

804436

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.479

High

806170

NMD3
60S ribosomal export protein NMD3

1

3

High-throughput

0.479

High

812632

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

829849

PHB1
Prohibitin-1

1

1

High-throughput

0.479

High

831833

RL33B
Large ribosomal subunit protein eL33B

1

1

High-throughput

0.479

High

835888

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

863879

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.479

High

879891

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

893055

PHB2
Prohibitin-2

1

1

High-throughput

0.479

High

893406

MNN10
Probable alpha-1,6-mannosyltransferase MNN10

1

1

High-throughput

0.479

High

902675

RL9B
Large ribosomal subunit protein uL6B

1

2

High-throughput

0.479

High

917686

LSG1
Large subunit GTPase 1

1

4

High-throughput

0.479

High

918333

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

1036291

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.479

High

1038397

RL21A
Large ribosomal subunit protein eL21A

1

1

High-throughput

0.479

High

1041879

RLI1
Translation initiation factor RLI1

1

1

High-throughput

0.479

High

1044217

ARX1
Probable metalloprotease ARX1

1

2

High-throughput

0.479

High

1046020

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.479

High

1046311

NOC4
Nucleolar complex protein 4

1

4

High-throughput

0.479

High

1046321

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

1046324

NEW1
[NU+] prion formation protein 1

1

2

High-throughput

0.479

High

1046335

RL21B
Large ribosomal subunit protein eL21B

1

1

High-throughput

0.479

High

1046337

RS21B
Small ribosomal subunit protein eS21B

1

1

High-throughput

0.479

High

1046338

RL11B
Large ribosomal subunit protein uL5B

1

1

High-throughput

0.479

High

154334

MBF1
Multiprotein-bridging factor 1

1

0

High-throughput

0.458

High

383362

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

403652

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.458

High

415052

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.458

High

416154

SYTC
Threonine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

420987

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.458

High

434439

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.458

High

438331

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.458

High

478642

IF2B
Eukaryotic translation initiation factor 2 subunit beta

1

0

High-throughput

0.458

High

503846

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.458

High

511595

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.458

High

511963

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.458

High

513911

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.458

High

514060

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.458

High

514361

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.458

High

514826

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

515324

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.458

High

534307

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

High-throughput

0.458

High

554374

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.458

High

555324

EI2BD
Translation initiation factor eIF2B subunit delta

1

0

High-throughput

0.458

High

569859

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

613631

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.458

High

642161

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

644984

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

672344

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.458

High

735865

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.458

High

736593

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.458

High

737772

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.458

High

739555

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

0

High-throughput

0.458

High

751478

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

758283

HCS1
DNA polymerase alpha-associated DNA helicase A

1

0

High-throughput

0.458

High

763622

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

783510

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

790289

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

792574

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

792747

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

0

High-throughput

0.458

High

796215

CDS1
Phosphatidate cytidylyltransferase

1

0

High-throughput

0.458

High

801107

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.458

High

802141

APM2
Adaptin medium chain homolog APM2

1

0

High-throughput

0.458

High

803438

RL14B
Large ribosomal subunit protein eL14B

1

0

High-throughput

0.458

High

807923

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.458

High

811578

MNN9
Mannan polymerase complexes subunit MNN9

1

0

High-throughput

0.458

High

814378

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.458

High

820960

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.458

High

823730

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

825271

YIK8
Putative zinc metalloproteinase YIL108W

1

0

High-throughput

0.458

High

831888

RS29B
Small ribosomal subunit protein uS14B

1

0

High-throughput

0.458

High

843321

RT18
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.458

High

844601

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

858551

AP3B
AP-3 complex subunit beta

1

0

High-throughput

0.458

High

879843

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.458

High

893221

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.458

High

916745

UFD1
Ubiquitin fusion degradation protein 1

1

0

High-throughput

0.458

High

917474

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.458

High

1018156

RL34A
Large ribosomal subunit protein eL34A

1

0

High-throughput

0.458

High

1038747

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

1039625

NOG1
Nucleolar GTP-binding protein 1

1

0

High-throughput

0.458

High

1044891

YHM2
Citrate/oxoglutarate carrier protein

1

0

High-throughput

0.458

High

1046297

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.458

High

1046298

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.458

High

1046300

RTN1
Reticulon-like protein 1

1

0

High-throughput

0.458

High

1046302

EIS1
Eisosome protein 1

1

0

High-throughput

0.458

High

1046303

SVF1
Ceramide-binding protein SVF1

1

0

High-throughput

0.458

High

1046308

DIC1
Mitochondrial dicarboxylate transporter

1

0

High-throughput

0.458

High

1046314

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

1046317

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

1046323

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

1046326

AP1G1
AP-1 complex subunit gamma-1

1

0

High-throughput

0.458

High

1046328

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.458

High

1046336

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

1046339

RS25A
Small ribosomal subunit protein eS25A

1

0

High-throughput

0.458

High

1046340

RS28A
Small ribosomal subunit protein eS28A

1

0

High-throughput

0.458

High

1046342

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

525071

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

527611

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

546183

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

742342

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

427609

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.437

High

427749

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.437

High

528870

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.437

High

597553

EF3A
Elongation factor 3A

1

2

High-throughput

0.437

High

632592

DBP3
ATP-dependent RNA helicase DBP3

1

1

High-throughput

0.437

High

632735

DBP4
ATP-dependent RNA helicase HCA4

1

3

High-throughput

0.437

High

633186

MAK11
Protein MAK11

1

2

High-throughput

0.437

High

677552

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

738254

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

2

High-throughput

0.437

High

746669

DRS1
ATP-dependent RNA helicase DRS1

1

2

High-throughput

0.437

High

754327

DCA13
Protein SOF1

1

2

High-throughput

0.437

High

780314

EBP2
rRNA-processing protein EBP2

1

1

High-throughput

0.437

High

791104

NOP4
Nucleolar protein 4

1

1

High-throughput

0.437

High

793526

MAK5
ATP-dependent RNA helicase MAK5

1

3

High-throughput

0.437

High

817626

UTP7
U3 small nucleolar RNA-associated protein 7

1

1

High-throughput

0.437

High

827601

RLP7
Ribosome biogenesis protein RLP7

1

1

High-throughput

0.437

High

863619

MNN11
Probable alpha-1,6-mannosyltransferase MNN11

1

1

High-throughput

0.437

High

864512

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.437

High

919774

YG5X
Putative methyltransferase YGR283C

1

1

High-throughput

0.437

High

923199

NOG2
Nucleolar GTP-binding protein 2

1

4

High-throughput

0.437

High

1039845

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.437

High

1043273

HAS1
ATP-dependent RNA helicase HAS1

1

3

High-throughput

0.437

High

1046243

UTP15
U3 small nucleolar RNA-associated protein 15

1

2

High-throughput

0.437

High

1046299

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.437

High

1046301

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.437

High

1046305

UTP13
U3 small nucleolar RNA-associated protein 13

1

4

High-throughput

0.437

High

1046306

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

High-throughput

0.437

High

1046313

UTP4
U3 small nucleolar RNA-associated protein 4

1

2

High-throughput

0.437

High

1046316

NOC3
Nucleolar complex-associated protein 3

1

3

High-throughput

0.437

High

1046318

NOP12
Nucleolar protein 12

1

1

High-throughput

0.437

High

1046319

BRX1
Ribosome biogenesis protein BRX1

1

4

High-throughput

0.437

High

1046325

YTM1
Ribosome biogenesis protein YTM1

1

2

High-throughput

0.437

High

1046329

MAK21
Ribosome biogenesis protein MAK21

1

4

High-throughput

0.437

High

1046330

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

1046331

NOP56
Nucleolar protein 56

1

2

High-throughput

0.437

High

1046332

NOP58
Nucleolar protein 58

1

2

High-throughput

0.437

High

780060

EAP1
Protein EAP1

1

0

High-throughput

0.269

Low

459162

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.249

Low

534138

MAK16
Protein MAK16

1

0

High-throughput

0.249

Low

632210

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.249

Low

632370

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.249

Low

677962

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.249

Low

688820

RFA3
Replication factor A protein 3

1

0

High-throughput

0.249

Low

700044

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.249

Low

700288

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.249

Low

745199

CDC13
Cell division control protein 13

1

0

Small-scale

0.249

Low

751877

SLA2
Protein SLA2

1

0

High-throughput

0.249

Low

751987

LHP1
La protein homolog

1

0

High-throughput

0.249

Low

758251

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.249

Low

763113

RRP1
Ribosomal RNA-processing protein 1

1

0

High-throughput

0.249

Low

764152

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

782440

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.249

Low

796678

IST2
Increased sodium tolerance protein 2

1

0

High-throughput

0.249

Low

803929

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.249

Low

804657

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.249

Low

805088

RPF1
Ribosome production factor 1

1

0

High-throughput

0.249

Low

814188

SEC72
Translocation protein SEC72

1

0

High-throughput

0.249

Low

816792

NOP16
Nucleolar protein 16

1

0

High-throughput

0.249

Low

858245

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

High-throughput

0.249

Low

863225

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.249

Low

864041

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.249

Low

864957

NOP9
Nucleolar protein 9

1

0

High-throughput

0.249

Low

865164

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.249

Low

871050

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.249

Low

918984

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

919165

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.249

Low

924327

NOP13
Nucleolar protein 13

1

0

High-throughput

0.249

Low

924625

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.249

Low

925275

YNF0
Uncharacterized protein YNL050C

1

0

High-throughput

0.249

Low

1028606

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

1036403

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.249

Low

1046294

BUD22
Bud site selection protein 22

1

0

High-throughput

0.249

Low

1046295

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.249

Low

1046296

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.249

Low

1046304

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.249

Low

1046307

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.249

Low

1046309

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.249

Low

1046310

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.249

Low

1046312

BFR2
Protein BFR2

1

0

High-throughput

0.249

Low

1046315

NOP6
Nucleolar protein 6

1

0

High-throughput

0.249

Low

1046320

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.249

Low

1046322

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.249

Low

1046327

SAS10
Something about silencing protein 10

1

0

High-throughput

0.249

Low

1046341

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025