Protein: PRP28
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8)

Gene: PRP28
Organism: Saccharomyces cerevisiae S288C
Interactions: 36
UniProt ID: P23394

Gene Ontology (top 5):
GO:0000384 - first spliceosomal transesterification activity
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

616107

PRP8
Pre-mRNA-splicing factor 8

3

5

Small-scale

0.827

High

616125

RUVB2
RuvB-like protein 2

2

5

High-throughput

0.759

High

557890

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.618

High

616106

BRR2
Pre-mRNA-splicing helicase BRR2

1

18

Small-scale

0.618

High

392057

H2A1
Histone H2A.1

2

4

High-throughput

0.588

High

356263

H4
Histone H4

1

8

High-throughput

0.575

High

616102

PRP28
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28

1

13

Small-scale

0.575

High

616117

RUVB1
RuvB-like protein 1

1

5

High-throughput

0.575

High

616119

TOS4
Protein TOS4

2

0

High-throughput

0.563

High

490386

HSP71
Heat shock protein SSA1

2

8

High-throughput

0.552

High

510311

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.552

High

616109

RV167
Reduced viability upon starvation protein 167

1

3

High-throughput

0.515

High

616112

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.513

High

616124

SWM1
Anaphase-promoting complex subunit SWM1

1

0

High-throughput

0.513

High

616103

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

616104

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

5

High-throughput

0.479

High

616108

SN114
Pre-mRNA-splicing factor SNU114

1

6

Small-scale

0.479

High

616116

NOP3
Serine/arginine

1

18

Small-scale

0.479

High

616121

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

616122

YRA1
RNA annealing protein YRA1

1

12

High-throughput

0.479

High

616123

CLF1
Pre-mRNA-splicing factor CLF1

1

14

Small-scale

0.479

High

616118

RU1C
U1 small nuclear ribonucleoprotein C

1

0

Small-scale

0.458

High

616120

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

367757

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

404497

RL7A
Large ribosomal subunit protein uL30A

1

3

High-throughput

0.445

High

493238

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

613635

RS3A2
Small ribosomal subunit protein eS1B

1

3

High-throughput

0.445

High

616105

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

616110

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

616111

RL13B
Large ribosomal subunit protein eL13B

1

2

High-throughput

0.445

High

616114

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.445

High

424352

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

555822

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

616115

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.426

High

616113

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024