Protein: SSK1
Osmolarity two-component system protein SSK1

Gene: SSK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: Q07084

Gene Ontology (top 5):
GO:0000156 - phosphorelay response regulator activity
GO:0005737 - cytoplasm
GO:0007234 - osmosensory signaling via phosphorelay pathway
GO:0030295 - protein kinase activator activity
GO:0031435 - mitogen-activated protein kinase kinase kinase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1058760

YPD1
Phosphorelay intermediate protein YPD1

14

6

Small-scale

0.983

High

921484

SSK2
MAP kinase kinase kinase SSK2

11

4

Small-scale

0.760

High

673754

SSK22
Serine/threonine-protein kinase SSK22

3

4

High-throughput

0.674

High

815009

SLN1
Osmosensing histidine protein kinase SLN1

1

17

Small-scale

0.647

High

1058759

SSK1
Osmolarity two-component system protein SSK1

1

18

Small-scale

0.618

High

364767

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.561

High

819920

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

464640

PBS2
MAP kinase kinase PBS2

1

0

High-throughput

0.530

High

722292

XPO1
Exportin-1

1

0

High-throughput

0.513

High

736049

SP110
Spindle pole body component 110

1

0

High-throughput

0.513

High

1027286

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

2

High-throughput

0.481

High

642479

MCK1
Protein kinase MCK1

1

0

High-throughput

0.480

High

741143

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

1058762

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

405148

LEU3
3-isopropylmalate dehydrogenase

1

1

High-throughput

0.457

High

358348

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.445

High

365202

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.445

High

386876

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

486326

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.445

High

525300

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

546454

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

580142

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.445

High

592525

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.445

High

742505

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

793354

SYG
Glycine--tRNA ligase 1, mitochondrial

1

2

High-throughput

0.445

High

802701

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.445

High

803698

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.445

High

836917

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

1058763

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

708317

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

708791

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

394938

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

450651

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.426

High

453817

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

684856

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

796187

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.426

High

817965

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

835899

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.426

High

367131

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.407

High

575526

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.407

High

597563

EF3A
Elongation factor 3A

1

3

High-throughput

0.407

High

603556

VATA
V-type proton ATPase catalytic subunit A

1

5

High-throughput

0.407

High

677826

ILV6
Acetolactate synthase small subunit, mitochondrial

1

1

High-throughput

0.407

High

734211

EF2
Elongation factor 2

1

1

High-throughput

0.407

High

755182

GCN1
eIF-2-alpha kinase activator GCN1

1

2

High-throughput

0.407

High

811176

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.407

High

836108

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.407

High

849558

GCN20
Protein GCN20

1

2

High-throughput

0.407

High

858076

RSSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.407

High

1028034

ACAC
Acetyl-CoA carboxylase

1

1

High-throughput

0.407

High

948669

ACT
Actin

2

0

High-throughput

0.305

High

603116

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.279

Low

745504

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.279

Low

1035132

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.279

Low

735573

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.261

Low

747705

ATO2
Ammonia transport outward protein 2

1

0

High-throughput

0.249

Low

826408

MPH1
ATP-dependent DNA helicase MPH1

1

0

High-throughput

0.249

Low

1058761

SAS10
Something about silencing protein 10

1

0

High-throughput

0.238

Low

455527

PMM
Phosphomannomutase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025