Protein: SPC24
Kinetochore protein SPC24

Gene: SPC24
Organism: Saccharomyces cerevisiae S288C
Interactions: 160
UniProt ID: Q04477

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
GO:0031134 - sister chromatid biorientation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

824871

NDC80
Kinetochore protein NDC80

27

0

Small-scale

0.941

High

755297

NUF2
Kinetochore protein NUF2

13

0

Small-scale

0.931

High

826817

DSN1
Kinetochore-associated protein DSN1

11

0

Small-scale

0.925

High

817026

SPC25
Kinetochore protein SPC25

27

0

Small-scale

0.737

High

850695

CENPT
Inner kinetochore subunit CNN1

8

0

Small-scale

0.723

High

926711

MPS1
Serine/threonine-protein kinase MPS1

4

1

Small-scale

0.689

High

814092

MTW1
Kinetochore-associated protein MTW1

5

0

Small-scale

0.686

High

1046706

SPC24
Kinetochore protein SPC24

5

0

Small-scale

0.679

High

917731

KNL1
Outer kinetochore KNL1 complex subunit SPC105

5

0

Small-scale

0.676

High

1046710

MMR1
Mitochondrial MYO2 receptor-related protein 1

3

0

High-throughput

0.617

High

1046712

HDA2
HDA1 complex subunit 2

3

0

High-throughput

0.617

High

1046721

SMC5
Structural maintenance of chromosomes protein 5

2

1

High-throughput

0.595

High

924102

CNM67
Chaotic nuclear migration protein 67

2

1

High-throughput

0.576

High

1046716

PRP11
Pre-mRNA-splicing factor PRP11

2

0

High-throughput

0.570

High

858398

STU2
Protein STU2

2

0

Small-scale

0.569

High

408349

GAL1
Galactokinase

2

0

Small-scale

0.569

High

797907

CENPU
Inner kinetochore subunit AME1

2

0

Small-scale

0.559

High

1046725

NSL1
Kinetochore-associated protein NSL1

2

0

High-throughput

0.547

High

736046

SP110
Spindle pole body component 110

2

0

Small-scale

0.528

High

825046

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.513

High

359065

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.500

High

439426

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.500

High

750777

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.493

High

555275

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.486

High

747758

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.486

High

1046713

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.486

High

850924

CHA4
Activatory protein CHA4

1

1

High-throughput

0.481

High

869275

TEA1
TY1 enhancer activator

1

1

High-throughput

0.481

High

1046717

ADY3
Accumulates dyads protein 3

1

1

High-throughput

0.481

High

546208

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.479

High

590718

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

597269

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.479

High

680048

CDC48
Cell division control protein 48

1

0

High-throughput

0.479

High

483806

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.460

High

624938

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

High-throughput

0.460

High

644985

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

Small-scale

0.460

High

678739

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.460

High

682891

MSH1
DNA mismatch repair protein MSH1, mitochondrial

1

0

High-throughput

0.460

High

745533

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.460

High

777114

BDF1
Bromodomain-containing factor 1

1

0

High-throughput

0.460

High

814380

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.460

High

823223

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

827007

MET28
Transcriptional activator of sulfur metabolism MET28

1

0

High-throughput

0.460

High

849875

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

High-throughput

0.460

High

897503

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.460

High

918290

POP6
Ribonucleases P/MRP protein subunit POP6

1

0

High-throughput

0.460

High

1037083

HAP5
Transcriptional activator HAP5

1

0

High-throughput

0.460

High

1046707

RSE1
Pre-mRNA-splicing factor RSE1

1

0

Small-scale

0.460

High

1046711

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.460

High

1046720

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.460

High

1046722

MPC54
Meiotic plaque component protein 54

1

0

Small-scale

0.460

High

1046723

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.460

High

1046724

SAS10
Something about silencing protein 10

1

0

High-throughput

0.460

High

1046726

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.460

High

708126

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

866065

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.458

High

919105

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.458

High

1046161

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

359527

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.457

High

456454

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

High-throughput

0.457

High

575519

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.457

High

742359

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

806216

SPC97
Spindle pole body component SPC97

1

1

High-throughput

0.445

High

921076

SPC98
Spindle pole body component SPC98

1

1

High-throughput

0.445

High

815774

SAP1
Protein SAP1

1

1

High-throughput

0.439

High

878741

ASNS1
Asparagine synthetase [glutamine-hydrolyzing] 1

1

1

Small-scale

0.439

High

381629

H2B2
Histone H2B.2

1

0

High-throughput

0.426

High

382331

H4
Histone H4

1

0

High-throughput

0.426

High

445369

CDC31
Cell division control protein 31

1

0

High-throughput

0.426

High

525091

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

549980

KAR1
Cell division control protein KAR1

1

0

High-throughput

0.426

High

686905

BUB2
Mitotic check point protein BUB2

1

0

High-throughput

0.426

High

734622

NUD1
Protein NUD1

1

0

High-throughput

0.426

High

740008

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

High-throughput

0.426

High

753039

SPC29
Spindle pole component 29

1

0

High-throughput

0.426

High

776712

ASK1
DASH complex subunit ASK1

1

0

High-throughput

0.426

High

780984

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.426

High

782557

NU133
Nucleoporin NUP133

1

0

High-throughput

0.426

High

795205

NU170
Nucleoporin NUP170

1

0

High-throughput

0.426

High

797255

HSL7
Protein arginine N-methyltransferase HSL7

1

0

High-throughput

0.426

High

807143

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

813853

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.426

High

817952

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

823502

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.426

High

864651

NU192
Nucleoporin NUP192

1

0

High-throughput

0.426

High

865482

BFA1
Mitotic check point protein BFA1

1

0

High-throughput

0.426

High

920685

TBG
Tubulin gamma chain

1

0

High-throughput

0.426

High

948649

ACT
Actin

1

0

High-throughput

0.426

High

1026826

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

1044092

NUP53
Nucleoporin NUP53

1

0

High-throughput

0.426

High

1044272

FIN1
Filament protein FIN1

1

0

High-throughput

0.426

High

1046728

SFI1
Protein SFI1

1

0

High-throughput

0.426

High

1046731

CENPI
Inner kinetochore subunit CTF3

1

0

High-throughput

0.426

High

577346

NSP1
Nucleoporin NSP1

1

1

High-throughput

0.407

High

877982

NUP57
Nucleoporin NUP57

1

2

High-throughput

0.407

High

886206

NU145
Nucleoporin NUP145

1

3

High-throughput

0.407

High

1035270

NUP49
Nucleoporin NUP49/NSP49

1

2

High-throughput

0.407

High

917793

MPS2
Monopolar spindle protein 2

7

0

Small-scale

0.391

High

779799

DYHC
Dynein heavy chain, cytoplasmic

2

0

High-throughput

0.319

High

672459

STE50
Protein STE50

2

0

Small-scale

0.310

High

737341

CDC12
Cell division control protein 12

2

0

High-throughput

0.310

High

919256

YG3A
Uncharacterized protein YGR130C

2

0

High-throughput

0.310

High

724305

ZIP1
Synaptonemal complex protein ZIP1

2

0

High-throughput

0.304

High

817222

FIR1
Factor interacting with REF2

2

0

Small-scale

0.304

High

864824

MPS3
Spindle pole body assembly component MPS3

2

0

High-throughput

0.300

High

737773

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.279

Low

1046730

GLT1
Glutamate synthase [NADH]

1

0

High-throughput

0.279

Low

735672

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.269

Low

1042555

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

High-throughput

0.269

Low

781337

DID4
DOA4-independent degradation protein 4

1

0

High-throughput

0.265

Low

367810

ENO1
Enolase 1

1

0

High-throughput

0.261

Low

405142

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

408590

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.261

Low

471436

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.261

Low

592492

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.261

Low

644839

CLH
Clathrin heavy chain

1

0

High-throughput

0.261

Low

701739

URA7
CTP synthase 1

1

0

High-throughput

0.261

Low

813570

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.261

Low

370502

STF1
F(1)-ATPase inhibitor STF1, mitochondrial

1

0

High-throughput

0.251

Low

569538

HAP4
Transcriptional activator HAP4

1

0

High-throughput

0.251

Low

673751

SSK22
Serine/threonine-protein kinase SSK22

1

0

Small-scale

0.251

Low

737041

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

795697

ECM13
Protein ECM13

1

0

High-throughput

0.251

Low

800361

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.251

Low

802533

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

814909

VPS52
Vacuolar protein sorting-associated protein 52

1

0

High-throughput

0.251

Low

816745

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.251

Low

817761

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

818337

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.251

Low

818674

YE16
Uncharacterized protein YER186C

1

0

High-throughput

0.251

Low

824668

BNR1
BNI1-related protein 1

1

0

High-throughput

0.251

Low

835552

BUD6
Bud site selection protein 6

1

0

Small-scale

0.251

Low

836231

MID1
Stretch-activated cation channel MID1

1

0

Small-scale

0.251

Low

849705

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

849849

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

864583

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

871019

SNAPN
Biogenesis of lysosome-related organelles complex 1 subunit SNN1

1

0

High-throughput

0.251

Low

917097

MDS3
Negative regulator of sporulation MDS3

1

0

Small-scale

0.251

Low

917778

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.251

Low

918767

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

1025034

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.251

Low

1043918

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

High-throughput

0.251

Low

1044249

SPO71
Prospore membrane adapter protein SPO71

1

0

Small-scale

0.251

Low

1046708

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

1046709

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

1046714

YL419
Putative ATP-dependent RNA helicase YLR419W

1

0

Small-scale

0.251

Low

1046715

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.251

Low

1046719

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

1046729

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

1046732

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.251

Low

1046733

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

1046718

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

Small-scale

0.249

Low

738559

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

756660

NIC96
Nucleoporin NIC96

1

0

High-throughput

0.232

Low

776543

NU120
Nucleoporin NUP120

1

0

High-throughput

0.232

Low

835955

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.232

Low

912752

NU188
Nucleoporin NUP188

1

0

High-throughput

0.232

Low

915412

NBP1
NAP1-binding protein

1

0

High-throughput

0.232

Low

1046727

BBP1
Spindle pole component BBP1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025