Protein: NOT5
General negative regulator of transcription subunit 5

Gene: NOT5
Organism: Saccharomyces cerevisiae S288C
Interactions: 75
UniProt ID: Q12514

Gene Ontology (top 5):
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636194

NOT1
General negative regulator of transcription subunit 1

14

4

Small-scale

0.982

High

409869

NOT2
General negative regulator of transcription subunit 2

8

8

Small-scale

0.974

High

410041

NOT3
General negative regulator of transcription subunit 3

5

2

Small-scale

0.921

High

713728

NOT4
General negative regulator of transcription subunit 4

11

2

Small-scale

0.754

High

865187

CAF40
Protein CAF40

9

4

Small-scale

0.751

High

1015705

NOT5
General negative regulator of transcription subunit 5

2

2

Small-scale

0.727

High

680071

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

5

6

Small-scale

0.721

High

759108

POP2
Poly(A) ribonuclease POP2

4

6

Small-scale

0.672

High

861148

CF130
Protein CAF130

3

0

Small-scale

0.623

High

805258

TAF1
Transcription initiation factor TFIID subunit 1

2

1

Small-scale

0.586

High

701155

SMY2
Protein SMY2

2

1

Small-scale

0.584

High

771524

NACB2
Nascent polypeptide-associated complex subunit beta-2

2

2

Small-scale

0.584

High

977547

TAF12
Transcription initiation factor TFIID subunit 12

2

1

Small-scale

0.584

High

971957

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

2

Small-scale

0.581

High

858593

TAF6
Transcription initiation factor TFIID subunit 6

2

0

Small-scale

0.559

High

495390

HSP72
Heat shock protein SSA2

2

4

High-throughput

0.552

High

513330

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.552

High

864643

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

1015183

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.536

High

515132

TAF13
Transcription initiation factor TFIID subunit 13

1

1

Small-scale

0.527

High

527083

TBP
TATA-box-binding protein

1

1

Small-scale

0.515

High

539432

KSS1
Mitogen-activated protein kinase KSS1

1

1

High-throughput

0.501

High

711018

HSL1
Probable serine/threonine-protein kinase HSL1

1

1

High-throughput

0.501

High

751108

RCK1
Serine/threonine-protein kinase RCK1

1

1

High-throughput

0.501

High

689844

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

1

High-throughput

0.494

High

811162

BBC1
Myosin tail region-interacting protein MTI1

1

1

High-throughput

0.494

High

413018

KAPB
cAMP-dependent protein kinase type 2

1

1

Small-scale

0.481

High

593097

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

1

Small-scale

0.481

High

635952

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

3

Small-scale

0.481

High

706081

NIP80
Protein NIP100

1

1

High-throughput

0.481

High

663761

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

728349

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.479

High

744720

TAF5
Transcription initiation factor TFIID subunit 5

1

1

Small-scale

0.479

High

774164

TM108
Protein TMA108

1

1

High-throughput

0.479

High

976007

GCN5
Histone acetyltransferase GCN5

1

3

Small-scale

0.479

High

978398

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

1014823

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

1015707

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

2

Small-scale

0.479

High

746802

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

772535

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

986235

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.460

High

375546

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

692102

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

Small-scale

0.458

High

757092

SKN7
Transcription factor SKN7

1

0

Small-scale

0.458

High

809608

RRP41
Exosome complex component SKI6

1

0

Small-scale

0.458

High

842092

SPT20
Transcription factor SPT20

1

0

Small-scale

0.458

High

865441

CSL4
Exosome complex component CSL4

1

0

Small-scale

0.458

High

970425

ADA2
Transcriptional adapter 2

1

0

Small-scale

0.458

High

884843

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

1

High-throughput

0.457

High

368534

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

492943

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

556399

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

695879

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

785300

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

860968

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.438

High

645165

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.437

High

701632

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

340333

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

361096

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

454519

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

810216

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

865953

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

700701

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.407

High

1015155

YP150
Putative serine/threonine-protein kinase YPL150W

1

0

High-throughput

0.261

Low

345272

STF1
F(1)-ATPase inhibitor STF1, mitochondrial

1

0

High-throughput

0.251

Low

859724

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.251

Low

1015706

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

630158

ELO2
Fatty acid elongase 2

1

0

High-throughput

0.249

Low

645726

RS7A
Small ribosomal subunit protein eS7A

1

0

Small-scale

0.249

Low

745961

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

775009

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

784265

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.249

Low

811602

YJY1
Uncharacterized protein YJR011C

1

0

High-throughput

0.249

Low

1015518

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024