Protein: PSB6
Proteasome subunit beta type-6 (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5)

Gene: PSB6, PRE7
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: P23724

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019774 - proteasome core complex, beta-subunit complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

645126

PSB4
Proteasome subunit beta type-4

12

20

Small-scale

0.975

High

662023

PSB5
Proteasome subunit beta type-5

7

20

Small-scale

0.958

High

661453

PSA2
Proteasome subunit alpha type-2

5

20

High-throughput

0.916

High

662044

PSA6
Proteasome subunit alpha type-6

5

18

High-throughput

0.912

High

662045

PSA4
Proteasome subunit alpha type-4

4

18

High-throughput

0.896

High

636541

PSA7
Probable proteasome subunit alpha type-7

4

20

High-throughput

0.892

High

662061

RPN5
26S proteasome regulatory subunit RPN5

4

20

Small-scale

0.892

High

662037

PSB1
Proteasome subunit beta type-1

3

19

High-throughput

0.855

High

636627

PSA1
Proteasome subunit alpha type-1

3

20

High-throughput

0.839

High

662016

PSB2
Proteasome subunit beta type-2

3

20

High-throughput

0.839

High

662024

PSB7
Proteasome subunit beta type-7

3

20

High-throughput

0.839

High

662025

PSA5
Proteasome subunit alpha type-5

3

17

High-throughput

0.839

High

662036

UMP1
Proteasome maturation factor UMP1

3

2

Small-scale

0.827

High

661371

PSA3
Proteasome subunit alpha type-3

2

20

High-throughput

0.776

High

662019

PSB3
Proteasome subunit beta type-3

2

20

High-throughput

0.754

High

662051

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

10

20

Small-scale

0.747

High

662050

BLM10
Proteasome activator BLM10

2

12

Small-scale

0.727

High

662020

FUB1
Silencing boundary-establishment protein FUB1

2

2

Small-scale

0.675

High

662040

RPN10
26S proteasome regulatory subunit RPN10

3

15

High-throughput

0.662

High

662015

PSB6
Proteasome subunit beta type-6

1

20

High-throughput

0.618

High

662021

CDC48
Cell division control protein 48

1

17

High-throughput

0.618

High

662030

PRS6A
26S proteasome regulatory subunit 6A

1

20

High-throughput

0.618

High

662031

PRS7
26S proteasome regulatory subunit 7 homolog

1

20

High-throughput

0.618

High

662046

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

662053

PRS8
26S proteasome regulatory subunit 8 homolog

1

20

High-throughput

0.618

High

662038

ECM29
Proteasome component ECM29

2

16

High-throughput

0.584

High

662048

PSMD9
Probable 26S proteasome regulatory subunit p27

2

0

Small-scale

0.582

High

662058

POC1
Proteasome chaperone 1

1

2

High-throughput

0.553

High

662033

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.518

High

662055

RPN4
Protein RPN4

1

0

Small-scale

0.518

High

660829

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

1

High-throughput

0.515

High

662032

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.514

High

662018

SSK22
Serine/threonine-protein kinase SSK22

1

2

Small-scale

0.494

High

314844

SEM1
26S proteasome complex subunit SEM1

1

2

High-throughput

0.479

High

578890

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.479

High

603013

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

662022

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

662026

RPN12
26S proteasome regulatory subunit RPN12

1

8

High-throughput

0.479

High

662027

RPN2
26S proteasome regulatory subunit RPN2

1

20

High-throughput

0.479

High

662028

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

662034

POC2
Proteasome assembly chaperone 2

1

2

High-throughput

0.479

High

662035

ATG8
Autophagy-related protein 8

1

8

High-throughput

0.479

High

662039

RPN1
26S proteasome regulatory subunit RPN1

1

20

High-throughput

0.479

High

662041

RPN3
26S proteasome regulatory subunit RPN3

1

11

High-throughput

0.479

High

662052

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

17

High-throughput

0.479

High

662054

TOM1
E3 ubiquitin-protein ligase TOM1

1

15

High-throughput

0.479

High

662056

RPN9
26S proteasome regulatory subunit RPN9

1

18

High-throughput

0.479

High

662057

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

662059

RPN8
26S proteasome regulatory subunit RPN8

1

20

High-throughput

0.479

High

432494

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.458

High

662049

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

662062

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

543879

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

662017

SIS1
Protein SIS1

1

5

High-throughput

0.445

High

662029

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

662043

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

662047

MLP2
Protein MLP2

1

3

High-throughput

0.437

High

662042

NU157
Nucleoporin NUP157

1

0

Small-scale

0.282

High

662060

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025