Protein: HSF
Heat shock transcription factor (HSTF) (Heat shock factor protein) (HSF)

Gene: HSF, HSF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P10961

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

522850

HSP71
Heat shock protein SSA1

6

19

Small-scale

0.730

High

525742

HSP72
Heat shock protein SSA2

4

19

Small-scale

0.702

High

534042

YAK1
Dual specificity protein kinase YAK1

3

5

Small-scale

0.667

High

534039

HSF
Heat shock transcription factor

1

17

Small-scale

0.647

High

534059

SKN7
Transcription factor SKN7

1

17

Small-scale

0.618

High

448618

SNF1
Carbon catabolite-derepressing protein kinase

2

1

Small-scale

0.614

High

534044

CSK22
Casein kinase II subunit alpha'

2

8

Small-scale

0.602

High

534073

GCN5
Histone acetyltransferase GCN5

2

6

High-throughput

0.601

High

534050

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

0

Small-scale

0.554

High

534064

RIM15
Serine/threonine-protein kinase RIM15

1

3

Small-scale

0.550

High

534069

PPP5
Serine/threonine-protein phosphatase T

1

1

Small-scale

0.536

High

534055

SPT7
SAGA complex subunit SPT7

1

6

High-throughput

0.536

High

534056

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

3

High-throughput

0.536

High

534057

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

2

High-throughput

0.536

High

534074

YL419
Putative ATP-dependent RNA helicase YLR419W

1

4

High-throughput

0.515

High

534048

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.513

High

534060

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.513

High

534072

SGF11
SAGA complex subunit SGF11

1

0

High-throughput

0.513

High

534077

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.513

High

534041

SCH9
Serine/threonine-protein kinase SCH9

1

3

Small-scale

0.501

High

534052

KNS1
Dual specificity protein kinase KNS1

1

6

Small-scale

0.501

High

479243

CDC6
Cell division control protein 6

1

0

High-throughput

0.493

High

534076

AHC1
Protein AHC1

1

1

Small-scale

0.481

High

481445

HSP73
Heat shock protein SSA3

1

18

High-throughput

0.479

High

534040

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

Small-scale

0.479

High

534043

HSC82
ATP-dependent molecular chaperone HSC82

1

10

High-throughput

0.479

High

534045

HSP74
Heat shock protein SSA4

1

18

High-throughput

0.479

High

534046

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

534051

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

534053

HOG1
Mitogen-activated protein kinase HOG1

1

8

Small-scale

0.479

High

534063

SSB2
Ribosome-associated molecular chaperone SSB2

1

18

Small-scale

0.479

High

534070

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

534078

MEX67
mRNA export factor MEX67

1

1

Small-scale

0.479

High

534062

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

534047

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

Small-scale

0.457

High

534049

KCC1
Calcium/calmodulin-dependent protein kinase I

1

2

Small-scale

0.457

High

534068

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

2

High-throughput

0.445

High

534061

CSK2C
Casein kinase II subunit beta'

1

1

Small-scale

0.439

High

534065

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.439

High

534066

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.426

High

534075

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.426

High

534071

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

534067

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.407

High

534054

SKT5
Chitin synthase regulator SKT5

1

0

High-throughput

0.269

Low

534058

SBE22
Protein SBE22

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025