Protein: APN1
Apurinic-apyrimidinic endonuclease 1 (AP endonuclease 1) (EC 3.1.21.-)

Gene: APN1
Organism: Saccharomyces cerevisiae S288C
Interactions: 39
UniProt ID: P22936

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0006284 - base-excision repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

381884

H4
Histone H4

2

0

High-throughput

0.559

High

653786

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.493

High

653797

H1
Histone H1

1

0

High-throughput

0.493

High

653800

IMA1
Importin subunit alpha

1

0

High-throughput

0.493

High

653805

YPD1
Phosphorelay intermediate protein YPD1

1

0

High-throughput

0.493

High

653809

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

437881

KAPC
cAMP-dependent protein kinase type 3

1

0

High-throughput

0.480

High

470101

SPS1
Sporulation-specific protein 1

1

0

High-throughput

0.480

High

653782

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

380975

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381408

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

653811

H2AZ
Histone H2A.Z

1

1

High-throughput

0.479

High

419605

H2A2
Histone H2A.2

1

0

High-throughput

0.458

High

448924

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

554555

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.458

High

653784

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

653785

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

653788

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

653789

BDF1
Bromodomain-containing factor 1

1

0

High-throughput

0.458

High

653790

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.458

High

653791

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.458

High

653792

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.458

High

653795

MPH1
ATP-dependent DNA helicase MPH1

1

0

High-throughput

0.458

High

653798

H3
Histone H3

1

0

High-throughput

0.458

High

653803

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

653806

SGO1
Shugoshin

1

0

High-throughput

0.458

High

653808

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

653810

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

543856

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

653794

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

653783

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

653793

RCK2
Serine/threonine-protein kinase RCK2

1

0

High-throughput

0.292

High

653801

PIR1
Cell wall mannoprotein PIR1

1

0

Small-scale

0.288

High

653796

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

653787

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

653802

IOC4
ISWI one complex protein 4

1

0

High-throughput

0.249

Low

653807

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.249

Low

653799

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

653804

NCS1
Calcium-binding protein NCS-1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025