Protein: NTH1
Endonuclease III homolog 1 (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase 1) (DNA glycosylase/AP lyase 1) (Endonuclease III-like glycosylase 1) (Redoxyendonuclease 1)

Gene: NTH1, NTG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 39
UniProt ID: P31378

Gene Ontology (top 5):
GO:0000703 - oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0003677 - DNA binding
GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

726010

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.536

High

459047

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.513

High

705744

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

0

High-throughput

0.513

High

726012

RFC2
Replication factor C subunit 2

1

0

High-throughput

0.513

High

726018

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.513

High

726020

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.513

High

726014

FPK1
Flippase kinase 1

1

2

Small-scale

0.501

High

726005

ARP2
Actin-related protein 2

1

1

High-throughput

0.489

High

408298

GAL1
Galactokinase

1

0

High-throughput

0.479

High

425115

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.479

High

486076

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.479

High

661593

MPCP
Mitochondrial phosphate carrier protein

1

0

High-throughput

0.479

High

673478

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.479

High

726013

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.479

High

726015

ACT
Actin

1

0

High-throughput

0.479

High

434907

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

706433

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

726019

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.479

High

726017

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

405049

LEU3
3-isopropylmalate dehydrogenase

1

1

High-throughput

0.457

High

671590

SCJ1
DnaJ-related protein SCJ1

1

2

High-throughput

0.457

High

481522

HSP73
Heat shock protein SSA3

1

4

High-throughput

0.445

High

510278

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.445

High

526131

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

544099

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

675790

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

726006

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

479969

PRTB
Cerevisin

1

0

High-throughput

0.279

Low

726009

FET3
Iron transport multicopper oxidase FET3

1

0

High-throughput

0.279

Low

726011

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

High-throughput

0.279

Low

726016

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.279

Low

386614

TBB
Tubulin beta chain

1

0

High-throughput

0.261

Low

585537

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

592078

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.261

Low

441765

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

504090

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

726007

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

726008

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

713212

SEC65
Signal recognition particle subunit SEC65

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025