Protein: CUE5
Ubiquitin-binding protein CUE5 (Coupling of ubiquitin conjugation to ER degradation protein 5)

Gene: CUE5
Organism: Saccharomyces cerevisiae S288C
Interactions: 38
UniProt ID: Q08412

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0006914 - autophagy
GO:0006995 - cellular response to nitrogen starvation
GO:0030674 - protein-macromolecule adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509745

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

7

1

Small-scale

0.970

High

850495

LSB3
LAS seventeen-binding protein 3

7

2

High-throughput

0.752

High

873811

DSK2
Ubiquitin domain-containing protein DSK2

2

0

Small-scale

0.743

High

393453

HSP82
ATP-dependent molecular chaperone HSP82

4

2

High-throughput

0.672

High

1063929

CUE5
Ubiquitin-binding protein CUE5

3

2

Small-scale

0.654

High

795570

ATG8
Autophagy-related protein 8

2

0

Small-scale

0.626

High

745050

YSC84
Protein YSC84

3

2

High-throughput

0.622

High

509932

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

1

High-throughput

0.618

High

525378

HSP71
Heat shock protein SSA1

3

0

High-throughput

0.606

High

815593

RSP5
E3 ubiquitin-protein ligase RSP5

2

0

Small-scale

0.585

High

628099

FKBP
FK506-binding protein 1

1

0

Small-scale

0.513

High

775995

TCTP
Translationally-controlled tumor protein homolog

1

0

Small-scale

0.513

High

656653

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

814292

RV167
Reduced viability upon starvation protein 167

1

2

High-throughput

0.501

High

1042988

THADA
tRNA

1

0

High-throughput

0.493

High

822396

HUA1
Proline-rich protein HUA1

1

0

High-throughput

0.486

High

580181

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

751014

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

Small-scale

0.479

High

623964

MYO2
Myosin-2

1

0

Small-scale

0.460

High

667123

CG22
G2/mitotic-specific cyclin-2

1

0

Small-scale

0.458

High

680120

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

748084

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

1063930

RPN8
26S proteasome regulatory subunit RPN8

1

0

Small-scale

0.458

High

1063931

RPN5
26S proteasome regulatory subunit RPN5

1

0

Small-scale

0.458

High

1063932

LAS17
Proline-rich protein LAS17

1

0

Small-scale

0.458

High

1051700

DON1
Donuts protein 1

1

2

High-throughput

0.457

High

742967

HSP79
Heat shock protein homolog SSE2

1

1

High-throughput

0.445

High

850231

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.437

High

1051548

NSE3
Non-structural maintenance of chromosome element 3

1

0

High-throughput

0.426

High

738711

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.265

Low

810674

SSN3
Meiotic mRNA stability protein kinase SSN3

1

0

High-throughput

0.261

Low

836352

BNI1
Protein BNI1

1

0

High-throughput

0.261

Low

506487

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

672734

BPH1
Beige protein homolog 1

1

0

High-throughput

0.249

Low

708390

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

721332

PSB7
Proteasome subunit beta type-7

1

0

Small-scale

0.249

Low

780807

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025