Protein: EMC1
ER membrane protein complex subunit 1

Gene: EMC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: P25574

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0006644 - phospholipid metabolic process
GO:0015914 - phospholipid transport
GO:0034975 - protein folding in endoplasmic reticulum
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

677102

EMC3
ER membrane protein complex subunit 3

2

2

Small-scale

0.754

High

677108

EMC5
ER membrane protein complex subunit 5

3

0

Small-scale

0.633

High

677113

EMC4
ER membrane protein complex subunit 4

1

2

High-throughput

0.618

High

677111

EMC2
ER membrane protein complex subunit 2

2

0

Small-scale

0.593

High

677104

SOP4
Protein SOP4

1

0

High-throughput

0.586

High

677122

EMC10
Endoplasmic reticulum membrane protein complex subunit 10

1

0

High-throughput

0.586

High

677103

PHO88
SRP-independent targeting protein 3

2

0

High-throughput

0.559

High

677123

EMC6
ER membrane protein complex subunit 6

1

0

Small-scale

0.529

High

554313

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

1

High-throughput

0.479

High

554400

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

1

High-throughput

0.479

High

577045

SEC63
Protein translocation protein SEC63

1

4

High-throughput

0.479

High

672134

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

1

High-throughput

0.479

High

677095

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

2

High-throughput

0.479

High

677100

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

1

High-throughput

0.479

High

677101

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

2

High-throughput

0.479

High

677105

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

2

High-throughput

0.479

High

677106

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

2

Small-scale

0.479

High

677110

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

2

High-throughput

0.479

High

677112

STE24
CAAX prenyl protease 1

1

1

High-throughput

0.479

High

636273

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.458

High

641353

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

677092

CWH43
Protein CWH43

1

0

High-throughput

0.458

High

677097

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

677099

SEC66
Translocation protein SEC66

1

0

High-throughput

0.458

High

677107

ELO3
Fatty acid elongase 3

1

0

High-throughput

0.458

High

677109

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.458

High

677115

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

677118

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

677119

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.458

High

677120

SPC2
Signal peptidase complex subunit 2

1

0

High-throughput

0.458

High

677125

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.458

High

677116

TOM5
Mitochondrial import receptor subunit TOM5

1

0

Small-scale

0.305

High

677096

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.282

High

677121

ATG39
Autophagy-related protein 39

1

0

High-throughput

0.269

Low

677124

GDIR
Rho GDP-dissociation inhibitor

1

0

High-throughput

0.251

Low

578933

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

677093

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

677094

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

677098

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.249

Low

677114

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

677117

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

High-throughput

0.249

Low

408463

GAL80
Galactose/lactose metabolism regulatory protein GAL80

1

0

Small-scale

0.213

Low


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Last updated: 11Aug2025