Protein: GAL80
Galactose/lactose metabolism regulatory protein GAL80

Gene: GAL80
Organism: Saccharomyces cerevisiae S288C
Interactions: 49
UniProt ID: P04387

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000166 - nucleotide binding
GO:0000431 - regulation of transcription from RNA polymerase II promoter by galactose
GO:0000435 - positive regulation of transcription from RNA polymerase II promoter by galactose
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

408451

GAL80
Galactose/lactose metabolism regulatory protein GAL80

7

0

Small-scale

0.919

High

408373

GAL4
Regulatory protein GAL4

27

1

Small-scale

0.769

High

408454

GAL3
Protein GAL3

15

1

Small-scale

0.764

High

408260

GAL1
Galactokinase

6

1

Small-scale

0.732

High

408456

CYC8
General transcriptional corepressor CYC8

2

0

Small-scale

0.577

High

408457

TUP1
General transcriptional corepressor TUP1

2

0

Small-scale

0.577

High

408462

PUT3
Proline utilization trans-activator

1

1

High-throughput

0.508

High

408484

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.493

High

408485

YG5B
Uncharacterized RNA-binding protein YGR250C

1

0

High-throughput

0.493

High

408488

UFO1
Ubiquitin ligase complex F-box protein UFO1

1

0

Small-scale

0.493

High

408492

MDM30
Mitochondrial distribution and morphology protein 30

1

0

Small-scale

0.493

High

408452

PHO2
Regulatory protein PHO2

1

0

High-throughput

0.486

High

408453

SWI5
Transcriptional factor SWI5

1

0

High-throughput

0.486

High

408459

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.486

High

408460

HCM1
Forkhead transcription factor HCM1

1

0

High-throughput

0.486

High

408461

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.486

High

408464

INO2
Protein INO2

1

0

High-throughput

0.486

High

408466

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.486

High

408467

RAEP
Rab proteins geranylgeranyltransferase component A

1

0

High-throughput

0.486

High

408468

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.486

High

408473

NNK1
Nitrogen network kinase 1

1

0

High-throughput

0.486

High

408474

UGPA2
Probable UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.486

High

408475

YEW0
Zinc finger protein YER130C

1

0

High-throughput

0.486

High

408476

MVP1
Sorting nexin MVP1

1

0

High-throughput

0.486

High

408477

GLDS1
Protein GDS1

1

0

High-throughput

0.486

High

408478

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.486

High

408480

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.486

High

408482

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.486

High

408483

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.486

High

408486

PRP38
Pre-mRNA-splicing factor 38

1

0

High-throughput

0.486

High

408487

SGF11
SAGA complex subunit SGF11

1

0

High-throughput

0.486

High

408489

DON1
Donuts protein 1

1

0

High-throughput

0.486

High

408493

MCA1
Metacaspase-1

1

0

High-throughput

0.486

High

408494

VTS1
RNA-binding protein VTS1

1

0

High-throughput

0.486

High

408495

MED2
Mediator of RNA polymerase II transcription subunit 2

1

0

High-throughput

0.486

High

408496

NKP1
Inner kinetochore subunit NKP1

1

0

High-throughput

0.486

High

408455

GAL2
Galactose transporter

1

0

High-throughput

0.458

High

408465

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

408471

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

408458

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

Small-scale

0.391

High

408469

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

Small-scale

0.391

High

408470

PRP8
Pre-mRNA-splicing factor 8

1

0

Small-scale

0.391

High

408479

DAS1
F-box protein DAS1

1

0

Small-scale

0.269

Low

408472

AP1B1
AP-1 complex subunit beta-1

1

0

High-throughput

0.265

Low

408481

ECL1
Extender of the chronological lifespan protein 1

1

0

High-throughput

0.265

Low

408490

ENT2
Epsin-2

1

0

High-throughput

0.265

Low

408491

HRD3
ERAD-associated E3 ubiquitin-protein ligase component HRD3

1

0

High-throughput

0.249

Low

408463

EMC1
ER membrane protein complex subunit 1

1

0

Small-scale

0.213

Low


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Last updated: 11Aug2025