Protein: VPS74
Vacuolar protein sorting-associated protein 74

Gene: VPS74
Organism: Saccharomyces cerevisiae S288C
Interactions: 45
UniProt ID: Q06385

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005797 - Golgi medial cisterna

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

735869

SAC1
Phosphatidylinositol-3-phosphatase SAC1

2

1

Small-scale

0.841

High

698156

KRE2
Glycolipid 2-alpha-mannosyltransferase

4

0

Small-scale

0.659

High

732196

COPG
Coatomer subunit gamma

2

7

Small-scale

0.602

High

836028

COPB
Coatomer subunit beta

2

5

Small-scale

0.602

High

836106

COPB2
Coatomer subunit beta'

2

7

Small-scale

0.602

High

850754

COPD
Coatomer subunit delta

2

3

Small-scale

0.602

High

922124

COPA
Coatomer subunit alpha

2

7

Small-scale

0.602

High

527749

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.584

High

825679

COPE
Coatomer subunit epsilon

2

0

Small-scale

0.577

High

1054923

VPS74
Vacuolar protein sorting-associated protein 74

1

2

Small-scale

0.575

High

792450

BOI1
BEM1-interacting protein 1

1

1

High-throughput

0.541

High

470155

SPS1
Sporulation-specific protein 1

1

0

High-throughput

0.513

High

763027

SPT7
SAGA complex subunit SPT7

1

0

High-throughput

0.513

High

536174

ARF1
ADP-ribosylation factor 1

1

1

Small-scale

0.501

High

780089

MNN4
Mannosyltransferase regulator 4

1

1

Small-scale

0.501

High

811557

MNN1
Alpha-1,3-mannosyltransferase MNN1

1

0

Small-scale

0.480

High

671153

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

806822

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

850216

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

5

High-throughput

0.479

High

1054925

AP3D
AP-3 complex subunit delta

1

4

High-throughput

0.479

High

603114

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

708255

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

727331

HS104
Heat shock protein 104

1

0

Small-scale

0.458

High

728661

OCH1
Initiation-specific alpha-1,6-mannosyltransferase

1

0

Small-scale

0.458

High

741129

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

792966

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

795548

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

803170

ECM29
Proteasome component ECM29

1

0

High-throughput

0.458

High

808916

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

1046177

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

1054927

H2AZ
Histone H2A.Z

1

0

High-throughput

0.458

High

525238

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

742462

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

818204

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

2

High-throughput

0.445

High

809291

MET30
F-box protein MET30

1

0

High-throughput

0.438

High

822484

PEP8
Carboxypeptidase Y-deficient protein 8

1

0

High-throughput

0.438

High

1054926

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.437

High

804480

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

819871

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

912451

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

592790

ERD1
Protein ERD1

1

0

Small-scale

0.288

High

1054928

YL149
Uncharacterized protein YLR149C

1

0

High-throughput

0.269

Low

797286

BMT2
25S rRNA

1

0

High-throughput

0.265

Low

1054924

YL352
F-box protein YLR352W

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025