HitPredict

Interactor 1: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Interactor 2: M4K5 (Q9Y4K4)
Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)
Gene: MAP4K5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 783 Hs			1 846
+	Hs
		1170693 TRI67_HUMAN (1-783): 0: 593: 100.00		M4K3_HUMAN (7-846): 0: 940: 64.55
+	Hs
		1039096 TRI67_HUMAN (1-783): 0: 593: 100.00		KCC2D_HUMAN (8-517): 1.77e-144: 437: 18.38
+	Hs
		1057174 TRI67_HUMAN (1-783): 0: 593: 100.00		MELK_HUMAN (20-615): 3.46e-137: 424: 19.44
+	Hs
		647914 TRI67_HUMAN (1-783): 0: 593: 100.00		MARK3_HUMAN (13-559): 3.08e-135: 422: 18.71
+	Hs
		1172307 TRI67_HUMAN (1-783): 0: 593: 100.00		KCC2A_HUMAN (8-488): 3.27e-138: 420: 19.26
+	Hs
		682189 TRI67_HUMAN (1-783): 0: 593: 100.00		AKT2_HUMAN (1-350): 8.02e-130: 398: 22.63
+	Hs
		1170538 TRI67_HUMAN (1-783): 0: 593: 100.00		MARK2_HUMAN (2-473): 3.58e-124: 394: 21.36
+	Hs
		681909 TRI67_HUMAN (1-783): 0: 593: 100.00		AKT1_HUMAN (12-346): 6.18e-125: 386: 22.38
+	Hs
		1023065 TRI67_HUMAN (1-783): 0: 593: 100.00		STK4_HUMAN (10-278): 1.36e-120: 375: 45.93
+	Hs
		1027387 TRI67_HUMAN (1-783): 0: 593: 100.00		STK3_HUMAN (1-408): 2.41e-120: 374: 32.45
+	Hs
		1172483 TRI67_HUMAN (1-783): 0: 593: 100.00		STK24_HUMAN (8-379): 1.48e-118: 368: 37.53
+	Hs
		1047941 TRI67_HUMAN (1-783): 0: 593: 100.00		KCC1A_HUMAN (15-322): 2.45e-111: 346: 25.24
+	Hs
		1172202 TRI67_HUMAN (1-783): 0: 593: 100.00		TNIK_HUMAN (14-295): 1.26e-72: 262: 45.73
+	Hs
		296414 TRI67_HUMAN (1-783): 0: 593: 100.00		STK10_HUMAN (15-286): 4.12e-66: 240: 45.46
+	Hs
		324829 TRI67_HUMAN (1-783): 0: 593: 100.00		M4K4_HUMAN (2-295): 4.04e-64: 236: 43.51
+	Hs
		1183133 TRI36_HUMAN (115-771): 5.52e-100: 327: 20.16		MARK2_HUMAN (2-473): 3.58e-124: 394: 21.36
+	Hs
		1282077 TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40		KCC2A_HUMAN (8-488): 3.27e-138: 420: 19.26
+	Hs
		1317547 TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57		KCC2A_HUMAN (8-488): 3.27e-138: 420: 19.26
+	Mm
		949339 TRI46_MOUSE (1-769): 7.66e-98: 322: 20.36		TNIK_MOUSE (14-295): 1.14e-72: 262: 45.73
+	Hs
		1318737 TRIM2_HUMAN (194-767): 1.51e-82: 280: 15.95		TNIK_HUMAN (14-295): 1.26e-72: 262: 45.73