Interactor 1: Q4KSH6 (Q4KSH6)
Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (SAPK/ERK kinase 1)
Gene: Map2k4
Interactor 2: M3K1 (Q62925)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)
Gene: Map3k1
Species: Rattus norvegicus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17568772 |
| Identification Methods | pull down |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0000165 - MAPK cascade GO:0004674 - protein serine/threonine kinase activity GO:0004708 - MAP kinase kinase activity GO:0005524 - ATP binding GO:0007254 - JNK cascade and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
