HitPredict

Interactor 1: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Interactor 2: HOME1 (Q9Z2Y3)
Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)
Gene: Homer1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30562941, 28634551
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0044325 - transmembrane transporter binding GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 817 Mm			1 366
+	Hs
		896619 NEB2_HUMAN (1-817): 4.8e-111: 359: 95.84		VASP_HUMAN (1-359): 1.5e-34: 132: 15.51
+	Mm
		98060 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		DESP_MOUSE (72-361): 3.82e-09: 60.4: 12.62
+	Hs
		936354 AFAD_HUMAN (397-798): 1.75e-38: 157: 18.69		MRCKA_HUMAN (1-348): 1.31e-70: 241: 17.13
+	Mm
		1223789 DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04		HOME1_MOUSE (1-366): 1.15e-85: 265: 100.00
+	Hs
		1399278 LRRC7_HUMAN (15-586): 7.55e-41: 164: 12.93		HOME3_HUMAN (3-366): 7.28e-70: 224: 48.91
+	Mm
		1223758 DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04		HOME2_MOUSE (1-362): 7.57e-76: 239: 51.11
+	Hs
		1348530 LNX1_HUMAN (236-773): 1.12e-33: 140: 11.17		HOME3_HUMAN (3-366): 7.28e-70: 224: 48.91
+	Mm
		1223700 DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04		HOME3_MOUSE (3-366): 2.42e-69: 223: 46.98
+	Hs
		63730 A5PKX9_HUMAN (493-589): 1.76e-15: 83.1: 36.08		HOME1_HUMAN (1-366): 4.31e-83: 258: 94.81
+	Hs
		157645 LNX1_HUMAN (236-773): 1.12e-33: 140: 11.17		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		936316 AFAD_HUMAN (397-798): 1.75e-38: 157: 18.69		ROCK1_HUMAN (1-364): 9.86e-39: 149: 16.58
+	Hs
		1399279 LRRC7_HUMAN (15-586): 7.55e-41: 164: 12.93		EP15R_HUMAN (115-364): 2.64e-32: 130: 16.67
+	Mm
		878602 DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04		CTRO_MOUSE (17-366): 5.93e-36: 141: 12.95
+	Rn
		97299 DLG4_RAT (381-806): 6.58e-31: 132: 11.04		CTRO_RAT (17-366): 1.6e-35: 140: 13.21
+	Mm
		1041721 DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04		ENAH_MOUSE (1-182): 5.85e-33: 132: 22.40
+	Hs
		157485 MAGI3_HUMAN (130-754): 1.86e-18: 93.2: 10.73		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		157751 MAGI1_HUMAN (453-794): 2.69e-17: 89.3: 12.64		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		157640 INADL_HUMAN (73-809): 4.3e-13: 75.4: 9.87		CTRO_HUMAN (12-364): 1.37e-45: 169: 13.04
+	Hs
		299755 MPDZ_HUMAN (44-808): 1.18e-18: 93.9: 10.50		VASP_HUMAN (1-359): 1.5e-34: 132: 15.51
+	Hs
		896616 MAGI1_HUMAN (453-794): 2.69e-17: 89.3: 12.64		VASP_HUMAN (1-359): 1.5e-34: 132: 15.51