HitPredict

Interactor 1: Q7K4B2 (Q7K4B2)
LD47540p (Lethal (2) k09848, isoform A) (Lethal (2) k09848, isoform B)
Gene: l(2)k09848

Interactor 2: WDR12 (Q9VKQ3)
Ribosome biogenesis protein WDR12 homolog
Gene: CG6724

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0030687 - preribosome, large subunit precursor
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 419 Dm			1 420
+	Sp
		314769 NSA1_SCHPO (19-334): 3.39e-103: 312: 22.19		YTM1_SCHPO (286-419): 2.08e-10: 64.1: 17.12
+	Hs
		1334151 POC1A_HUMAN (86-395): 6.96e-57: 194: 11.15		POC1B_HUMAN (248-420): 7.15e-43: 158: 20.46
+	Sc
		673576 NSA1_YEAST (107-359): 3.72e-65: 217: 23.81		NLE1_YEAST (290-419): 1.22e-28: 119: 20.86
+	Hs
		965071 WDR5_HUMAN (223-398): 1.4e-28: 116: 14.77		WDR5B_HUMAN (180-419): 1.29e-59: 198: 23.46
+	Hs
		209230 WDR5_HUMAN (223-398): 1.4e-28: 116: 14.77		PRP4_HUMAN (136-418): 8.79e-56: 193: 17.45
+	Hs
		1180240 SMU1_HUMAN (86-349): 9.64e-28: 116: 11.46		FBXW7_HUMAN (176-419): 3.99e-53: 190: 26.83
+	Hs
		965141 WDR5_HUMAN (223-398): 1.4e-28: 116: 14.77		FBXW7_HUMAN (176-419): 3.99e-53: 190: 26.83
+	Sc
		917582 NSA1_YEAST (107-359): 3.72e-65: 217: 23.81		YTM1_YEAST (337-411): 2.53e-11: 67.1: 22.67
+	Dm
		1463899 WDS_DROME (223-398): 3.08e-28: 115: 14.21		WDS_DROME (239-418): 7.13e-48: 169: 26.23
+	Hs
		965276 WDR5_HUMAN (223-398): 1.4e-28: 116: 14.77		NLE1_HUMAN (239-419): 4.77e-46: 167: 23.00
+	Hs
		965225 SKI8_HUMAN (105-315): 3.84e-61: 201: 18.48		WDR5_HUMAN (4-135): 1.85e-16: 81.8: 13.24
+	Dm
		1463923 WDS_DROME (223-398): 3.08e-28: 115: 14.21		FBXW7_DROME (2-274): 9.49e-43: 162: 14.89
+	Sc
		673545 NLE1_YEAST (81-396): 2.59e-37: 143: 10.03		NLE1_YEAST (290-419): 1.22e-28: 119: 20.86
+	Hs
		845264 WDR5_HUMAN (223-398): 1.4e-28: 116: 14.77		LIS1_HUMAN (278-419): 1.5e-32: 128: 18.88
+	Hs
		845346 KTNB1_HUMAN (5-228): 2.2e-26: 113: 12.83		LIS1_HUMAN (278-419): 1.5e-32: 128: 18.88
+	Hs
		965223 WDR5_HUMAN (223-398): 1.4e-28: 116: 14.77		WDR12_HUMAN (251-419): 1.89e-23: 103: 22.22
+	Hs
		965151 WDR5_HUMAN (223-398): 1.4e-28: 116: 14.77		SNR40_HUMAN (322-416): 1.07e-17: 85.6: 18.75
+	Hs
		964797 WDR5_HUMAN (223-398): 1.4e-28: 116: 14.77		WDR5_HUMAN (4-135): 1.85e-16: 81.8: 13.24
+	Sp
		1068486 TUP12_SCHPO (3-224): 8.08e-28: 117: 13.12		TUP11_SCHPO (317-419): 1.92e-11: 67.9: 15.60