HitPredict

Interactor 1: Q7KSB7 (Q7KSB7)
Apoptotic signal-regulating kinase 1, isoform B (EC 2.7.11.25)
Gene: Ask1

Interactor 2: Q9W0K9 (Q9W0K9)
LD10220p
Gene: DmelCG9205

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1196 Dm			1 224
+	Dm
		1471914 Q9VDS9_DROME (1-1196): 0: 1083: 100.00		Q9W0K9_DROME (1-224): 1.14e-68: 211: 100.00
+	Dm
		53620 Q9VDS9_DROME (1-1196): 0: 1083: 100.00		A1Z814_DROME (11-216): 2.28e-38: 142: 20.72
+	Dm
		1269012 Q7KSB7_DROME (1-1196): 0: 1082: 100.00		Q9Y128_DROME (13-214): 2.49e-33: 127: 19.31
+	Hs
		728401 M3K5_HUMAN (2-1133): 0: 932: 41.10		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Mm
		204222 M3K5_MOUSE (2-1133): 0: 932: 41.14		AKT1_MOUSE (13-164): 1.64e-34: 130: 11.84
+	Hs
		728615 M3K5_HUMAN (2-1133): 0: 932: 41.10		AKT2_HUMAN (12-218): 2.34e-34: 129: 12.80
+	Hs
		1270568 MARK2_HUMAN (370-1128): 1.48e-157: 491: 13.71		CERT_HUMAN (14-219): 3.43e-39: 144: 18.38
+	Hs
		728310 MARK2_HUMAN (370-1128): 1.48e-157: 491: 13.71		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		692176 MARK3_HUMAN (372-1128): 1e-148: 467: 13.97		CERT_HUMAN (14-219): 3.43e-39: 144: 18.38
+	Hs
		1453880 MARK1_HUMAN (388-1128): 1.9e-143: 454: 14.78		CERT_HUMAN (14-219): 3.43e-39: 144: 18.38
+	Hs
		909263 NEK4_HUMAN (418-1074): 1.53e-119: 392: 18.95		CERT_HUMAN (14-219): 3.43e-39: 144: 18.38
+	Hs
		728491 AKT3_HUMAN (309-717): 4.27e-123: 389: 21.31		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		728630 AKT3_HUMAN (309-717): 4.27e-123: 389: 21.31		AKT2_HUMAN (12-218): 2.34e-34: 129: 12.80
+	Hs
		728252 KS6A1_HUMAN (373-813): 2.22e-108: 359: 17.29		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		331757 KS6A2_HUMAN (401-813): 1.04e-111: 368: 21.50		MTMR5_HUMAN (10-122): 7.13e-29: 115: 26.55
+	Hs
		728208 STK3_HUMAN (389-852): 7.59e-103: 336: 25.37		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		728203 STK4_HUMAN (396-677): 4.7e-101: 331: 35.46		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Sc
		1030272 BCK1_YEAST (389-675): 2.77e-41: 168: 37.33		OSH2_YEAST (9-155): 7.12e-27: 110: 20.67
+	Hs
		728050 AKT2_HUMAN (201-330): 2e-17: 88.7: 14.82		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Mm
		728507 AKT1_MOUSE (201-344): 5.13e-17: 87.6: 11.57		AKT1_MOUSE (13-164): 1.64e-34: 130: 11.84