HitPredict

Interactor 1: Q9VDS9 (Q9VDS9)
Apoptotic signal-regulating kinase 1, isoform C (EC 2.7.11.25)
Gene: Ask1

Interactor 2: Q9W0K9 (Q9W0K9)
LD10220p
Gene: DmelCG9205

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1363 Dm			1 224
+	Dm
		53620 Q9VDS9_DROME (1-1363): 0: 1293: 100.00		A1Z814_DROME (11-216): 2.28e-38: 142: 20.72
+	Mm
		204222 M3K5_MOUSE (3-1300): 0: 1179: 39.67		AKT1_MOUSE (13-164): 1.64e-34: 130: 11.84
+	Hs
		728401 M3K5_HUMAN (3-1300): 0: 1178: 39.74		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		728615 M3K5_HUMAN (3-1300): 0: 1178: 39.74		AKT2_HUMAN (12-218): 2.34e-34: 129: 12.80
+	Dm
		1269008 Q7KSB7_DROME (168-1363): 0: 1063: 100.00		Q9W0K9_DROME (1-224): 1.14e-68: 211: 100.00
+	Dm
		1269012 Q7KSB7_DROME (168-1363): 0: 1063: 100.00		Q9Y128_DROME (13-214): 2.49e-33: 127: 19.31
+	Hs
		1270568 MARK2_HUMAN (537-1267): 8.74e-140: 448: 14.61		CERT_HUMAN (14-219): 3.43e-39: 144: 18.38
+	Hs
		728310 MARK2_HUMAN (537-1267): 8.74e-140: 448: 14.61		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		692176 MARK3_HUMAN (540-1261): 1.41e-131: 425: 13.11		CERT_HUMAN (14-219): 3.43e-39: 144: 18.38
+	Hs
		909263 NEK4_HUMAN (585-1241): 1.26e-117: 390: 18.95		CERT_HUMAN (14-219): 3.43e-39: 144: 18.38
+	Hs
		728491 AKT3_HUMAN (476-884): 3.71e-122: 390: 21.31		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		728630 AKT3_HUMAN (476-884): 3.71e-122: 390: 21.31		AKT2_HUMAN (12-218): 2.34e-34: 129: 12.80
+	Hs
		331757 KS6A2_HUMAN (570-1194): 2.4e-118: 389: 17.56		MTMR5_HUMAN (10-122): 7.13e-29: 115: 26.55
+	Hs
		728252 KS6A1_HUMAN (556-1236): 3.09e-111: 369: 14.75		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		728208 STK3_HUMAN (556-1019): 1.75e-101: 334: 25.37		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		728203 STK4_HUMAN (537-844): 9.19e-100: 329: 32.79		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Sc
		1030272 BCK1_YEAST (556-842): 3.28e-41: 168: 37.33		OSH2_YEAST (9-155): 7.12e-27: 110: 20.67
+	Hs
		728050 AKT2_HUMAN (368-497): 4.52e-17: 87.9: 14.82		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50
+	Hs
		728049 AKT1_HUMAN (368-511): 2.15e-16: 86: 11.41		AKT1_HUMAN (13-164): 3.49e-35: 131: 12.50