HitPredict

Interactor 1: RIC8B (Q80XE1)
Chaperone Ric-8B (Synembryn-B)
Gene: RIC8B

Interactor 2: GNAL (Q8CGK7)
Guanine nucleotide-binding protein G(olf) subunit alpha (EC 3.6.5.-) (Adenylate cyclase-stimulating G alpha protein, olfactory type)
Gene: GNAL

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	15829631, 18462949
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	G-alpha~Ric8
Common GO terms	GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway GO:0007608 - sensory perception of smell
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 520 Mm			1 381
+	Hs
		989806 RIC8B_HUMAN (1-520): 0: 731: 97.12		GNAS2_HUMAN (1-381): 7.81e-169: 478: 76.52
+	Hs
		418753 RIC8B_HUMAN (1-520): 0: 731: 97.12		GNAI2_HUMAN (1-381): 2.7e-164: 465: 38.64
+	Hs
		893533 RIC8B_HUMAN (1-520): 0: 731: 97.12		GNAQ_HUMAN (11-381): 3.75e-161: 457: 38.81
+	Hs
		989882 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAI1_HUMAN (1-381): 1.17e-165: 469: 39.01
+	Hs
		418747 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAI2_HUMAN (1-381): 2.7e-164: 465: 38.64
+	Hs
		618486 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAZ_HUMAN (1-380): 2.32e-164: 465: 37.70
+	Hs
		476042 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAI3_HUMAN (1-381): 2.21e-162: 460: 38.74
+	Hs
		482641 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAO_HUMAN (1-381): 2.28e-162: 460: 39.69
+	Hs
		893526 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAQ_HUMAN (11-381): 3.75e-161: 457: 38.81
+	Hs
		716055 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNA11_HUMAN (11-381): 1.21e-157: 449: 38.01
+	Hs
		1125934 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNA13_HUMAN (4-380): 5.86e-154: 440: 34.81
+	Ce
		908551 RIC8_CAEEL (1-482): 1.74e-177: 513: 23.92		GNAO_CAEEL (1-381): 6.52e-159: 452: 39.69
+	Ce
		1427797 RIC8_CAEEL (1-482): 1.74e-177: 513: 23.92		GPA16_CAEEL (1-381): 1.18e-150: 431: 39.27
+	Dm
		631767 RIC8_DROME (3-465): 6.69e-169: 491: 30.68		GNAI_DROME (1-381): 4.44e-154: 439: 39.27