HitPredict

Interactor 1: ECSIT (Q9BQ95)
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC)
Gene: ECSIT

Interactor 2: ACAD9 (Q9H845)
Complex I assembly factor ACAD9, mitochondrial (Acyl-CoA dehydrogenase family member 9) (ACAD-9) (EC 1.3.8.-)
Gene: ACAD9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	24344204, 20816094, 32877691, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0032981 - mitochondrial respiratory chain complex I assembly
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 621
+	Mm
		1225037 ECSIT_MOUSE (1-431): 0: 684: 73.56		ACAD9_MOUSE (1-619): 0: 721: 85.71
+	Hs
		832930 ECSIT_HUMAN (1-431): 0: 698: 100.00		ACADV_HUMAN (23-617): 0: 609: 45.59
+	Hs
		1273115 ECSIT_HUMAN (1-431): 0: 698: 100.00		GCDH_HUMAN (57-442): 6.48e-122: 369: 26.79