HitPredict

Interactor 1: KBTB7 (Q8WVZ9)
Kelch repeat and BTB domain-containing protein 7
Gene: KBTBD7

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.900

Property	Details
Experiments	30190310, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 684 Hs			1 701
+	Hs
		1339590 KBTB8_HUMAN (42-624): 1.65e-171: 505: 28.14		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1290314 KBTB6_HUMAN (1-674): 7.4e-161: 480: 89.76		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459082 KLHL3_HUMAN (174-683): 8.75e-55: 199: 12.84		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		329116 KLHL2_HUMAN (437-683): 5.33e-49: 183: 14.39		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1247781 KLH17_HUMAN (176-683): 1.03e-47: 180: 14.05		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1121548 KEAP1_HUMAN (470-682): 1.89e-37: 150: 15.42		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1333284 KLH23_HUMAN (40-557): 1.8e-37: 149: 23.63		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		161311 ENC1_HUMAN (21-526): 1.65e-37: 149: 24.91		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459087 KLH20_HUMAN (326-483): 4.96e-23: 106: 18.87		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459091 IPP_HUMAN (311-482): 3.23e-23: 106: 16.38		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1454623 KLHL9_HUMAN (312-482): 7.39e-22: 102: 16.57		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1454747 KLH13_HUMAN (326-482): 6.65e-21: 99.6: 16.88		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1199049 KLH12_HUMAN (510-684): 1.5e-18: 91.9: 12.43		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1312883 KLHL7_HUMAN (441-603): 1.66e-18: 91.7: 15.56		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1247815 KLH24_HUMAN (315-485): 2.17e-16: 84.9: 18.02		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1235393 KLH10_HUMAN (551-683): 3.01e-15: 81.5: 14.10		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1200022 KLH26_HUMAN (498-678): 2.66e-13: 75.2: 10.88		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1430059 KLH25_HUMAN (511-684): 6.26e-11: 67.5: 14.37		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459084 KLH21_HUMAN (536-680): 2.32e-10: 65.6: 15.53		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1452115 KLH28_HUMAN (276-433): 1.25e-09: 63.4: 13.42		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00