HitPredict

Interactor 1: Q9V455 (Q9V455)
Importin subunit alpha
Gene: Kap-alpha3

Interactor 2: Q9VGL0 (Q9VGL0)
LD43047p
Gene: DmelCG14712

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 514 Dm			1 1266
+	Hs
		68005 IMA4_HUMAN (5-514): 6.23e-157: 458: 67.38		P121C_HUMAN (262-1114): 1.7e-27: 123: 14.11
+	Hs
		76075 IMA4_HUMAN (5-514): 6.23e-157: 458: 67.38		B4DET5_HUMAN (302-1114): 7.34e-28: 123: 14.42
+	Hs
		68006 IMA3_HUMAN (3-514): 1.04e-155: 455: 65.57		P121C_HUMAN (262-1114): 1.7e-27: 123: 14.11
+	Hs
		76076 IMA3_HUMAN (3-514): 1.04e-155: 455: 65.57		B4DET5_HUMAN (302-1114): 7.34e-28: 123: 14.42
+	Hs
		68012 IMA1_HUMAN (2-514): 1.22e-147: 435: 48.29		P121C_HUMAN (262-1114): 1.7e-27: 123: 14.11
+	Hs
		76104 IMA1_HUMAN (2-514): 1.22e-147: 435: 48.29		B4DET5_HUMAN (302-1114): 7.34e-28: 123: 14.42
+	Hs
		910821 IMA1_HUMAN (2-514): 1.22e-147: 435: 48.29		NUP98_HUMAN (955-1256): 1.51e-23: 110: 17.65
+	Hs
		138745 IMA4_HUMAN (5-514): 6.23e-157: 458: 67.38		P121A_HUMAN (268-1258): 4.68e-14: 79.7: 9.86
+	Hs
		142603 IMA3_HUMAN (3-514): 1.04e-155: 455: 65.57		P121A_HUMAN (268-1258): 4.68e-14: 79.7: 9.86
+	Hs
		138638 IMA4_HUMAN (5-514): 6.23e-157: 458: 67.38		NU214_HUMAN (605-1257): 4.31e-11: 69.9: 12.69
+	Ce
		1019138 IMA3_CAEEL (4-514): 2.7e-147: 433: 59.73		P91457_CAEEL (612-1239): 2.77e-18: 93.4: 17.01
+	Hs
		911050 IMA1_HUMAN (2-514): 1.22e-147: 435: 48.29		P121A_HUMAN (268-1258): 4.68e-14: 79.7: 9.86
+	Hs
		253676 IMA7_HUMAN (4-514): 7.61e-147: 433: 44.70		P121A_HUMAN (268-1258): 4.68e-14: 79.7: 9.86
+	Hs
		911046 IMA1_HUMAN (2-514): 1.22e-147: 435: 48.29		MBD6_HUMAN (136-852): 3.46e-09: 63.6: 8.37
+	Sc
		634272 IMA1_YEAST (5-514): 2.67e-141: 419: 42.59		NUP1_YEAST (429-961): 2.86e-11: 70.2: 15.46
+	Sc
		1035264 IMA1_YEAST (5-514): 2.67e-141: 419: 42.59		NUP49_YEAST (899-1150): 2.98e-11: 69.5: 17.32
+	Sc
		1037972 IMA1_YEAST (5-514): 2.67e-141: 419: 42.59		NU116_YEAST (336-1098): 2.56e-10: 67.2: 12.65
+	Sp
		313992 IMA2_SCHPO (2-514): 5.19e-141: 418: 42.78		NU124_SCHPO (593-1046): 1.66e-10: 68: 20.73
+	Sc
		877973 IMA1_YEAST (5-514): 2.67e-141: 419: 42.59		NUP57_YEAST (949-1233): 9.32e-10: 64.9: 21.31
+	Sc
		1037951 IMA1_YEAST (5-514): 2.67e-141: 419: 42.59		NU100_YEAST (878-1245): 1.47e-09: 64.8: 14.36