Interactor 1: SOCS2 (O14508)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)
Gene: SOCS2
Interactor 2: STA5B (P51692)
Signal transducer and activator of transcription 5B
Gene: STAT5B
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28883622 |
| Identification Methods | affinity chromatography technology, proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~SH2, SH2~STAT_linker, SH2~SOCS_box |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0007595 - lactation GO:0019221 - cytokine-mediated signaling pathway and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
