HitPredict

Interactor 1: SYNEM (O15061)
Synemin (Desmuslin)
Gene: SYNM

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	15872089
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1565 Hs			1 906
+	Mm
		651546 SYNEM_MOUSE (1-1555): 0: 1220: 69.14		CBL_MOUSE (1-906): 0: 851: 91.59
+	Hs
		385053 K1C14_HUMAN (9-349): 1.21e-141: 446: 23.98		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		651286 K1C17_HUMAN (6-328): 7.14e-138: 434: 26.54		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		476268 K1C16_HUMAN (7-336): 6.4e-136: 430: 25.68		CBL_HUMAN (1-906): 0: 882: 100.00
+	Mm
		59813 SYNEM_MOUSE (1-1555): 0: 1220: 69.14		TITIN_MOUSE (404-902): 1.99e-13: 77.3: 11.34
+	Hs
		651359 K2C79_HUMAN (3-325): 1.91e-65: 234: 18.65		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		651220 K2C6C_HUMAN (4-325): 7.01e-62: 224: 19.44		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		407253 K2C6B_HUMAN (4-325): 1.21e-61: 223: 19.44		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		566333 K2C5_HUMAN (4-325): 5.04e-61: 222: 18.83		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		385239 K2C6A_HUMAN (3-325): 1.15e-60: 221: 19.39		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		474478 VIME_HUMAN (11-320): 2.96e-31: 131: 33.44		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		651441 KRT84_HUMAN (60-388): 4.91e-16: 85.6: 12.68		CBL_HUMAN (1-906): 0: 882: 100.00
+	Hs
		475662 K1C19_HUMAN (6-330): 8.6e-134: 421: 23.01		ASPP1_HUMAN (460-843): 3.23e-10: 66.1: 12.69
+	Hs
		215895 VIME_HUMAN (11-320): 2.96e-31: 131: 33.44		SYNJ1_HUMAN (391-793): 3.14e-10: 66.5: 11.84
+	Hs
		551616 AINX_HUMAN (11-318): 1.33e-23: 108: 32.58		NFH_HUMAN (571-860): 9.92e-10: 64.5: 11.72
+	Hs
		215906 PERI_HUMAN (11-320): 1.19e-22: 105: 31.83		SYNJ1_HUMAN (391-793): 3.14e-10: 66.5: 11.84
+	Hs
		451110 NFL_HUMAN (11-318): 3.3e-23: 107: 29.87		NFH_HUMAN (571-860): 9.92e-10: 64.5: 11.72
+	Hs
		833341 PERI_HUMAN (11-320): 1.19e-22: 105: 31.83		ASPP1_HUMAN (460-843): 3.23e-10: 66.1: 12.69
+	Hs
		551604 DESM_HUMAN (11-320): 1.6e-20: 99: 31.29		NFH_HUMAN (571-860): 9.92e-10: 64.5: 11.72
+	Hs
		451320 NFM_HUMAN (4-318): 3.88e-17: 89.7: 27.36		NFH_HUMAN (571-860): 9.92e-10: 64.5: 11.72