HitPredict

Interactor 1: SOCS1 (O15524)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)
Gene: SOCS1

Interactor 2: DAB1 (O75553)
Disabled homolog 1
Gene: DAB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 29991678, 17974915
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT
GO:0043231 - intracellular membrane-bounded organelle
GO:0046426 - negative regulation of receptor signaling pathway via JAK-STAT
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 211
Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025