HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: M2OM (Q02978)
Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11)
Gene: SLC25A11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32929329, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 314
+	Hs
		226942 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TXTP_HUMAN (13-310): 1.49e-88: 269: 21.67
+	Hs
		227780 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SCMC1_HUMAN (109-309): 1.16e-46: 165: 19.40
+	Hs
		227774 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SCMC2_HUMAN (14-206): 1.63e-45: 162: 21.94
+	Hs
		228966 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DIC_HUMAN (14-207): 1.66e-30: 118: 20.92
+	Hs
		229010 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		S2513_HUMAN (3-122): 5.08e-23: 101: 20.83
+	Hs
		858319 HOIL1_HUMAN (12-448): 5.59e-68: 227: 16.36		TXTP_HUMAN (13-310): 1.49e-88: 269: 21.67
+	Hs
		226076 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		S2512_HUMAN (3-122): 4.43e-20: 92.6: 19.17
+	Hs
		226378 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT1_HUMAN (7-109): 1.71e-11: 65.6: 20.19
+	Hs
		226379 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15
+	Hs
		226250 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45
+	Hs
		1317097 HOIL1_HUMAN (12-448): 5.59e-68: 227: 16.36		S2513_HUMAN (3-122): 5.08e-23: 101: 20.83
+	Hs
		476538 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		S2513_HUMAN (3-122): 5.08e-23: 101: 20.83