HitPredict

Interactor 1: SRGP2 (O75044)
SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)
Gene: SRGAP2

Interactor 2: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031267 - small GTPase binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 140
+	Hs
		430203 RHG29_HUMAN (20-1041): 7.19e-98: 339: 15.37		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		430224 RHG17_HUMAN (244-1052): 2.89e-79: 280: 13.68		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		430167 MYO9B_HUMAN (101-929): 1.2e-75: 276: 13.52		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		430021 BCR_HUMAN (25-664): 1.36e-75: 274: 14.96		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		70642 MYO9A_HUMAN (80-935): 9.4e-73: 267: 14.92		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		430214 RHG21_HUMAN (200-1027): 2.03e-71: 263: 13.52		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		430262 RHG24_HUMAN (357-975): 1.55e-72: 258: 16.81		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		430350 RHG35_HUMAN (502-649): 2.56e-17: 90.1: 31.76		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		430200 RHGBB_HUMAN (504-671): 4.99e-18: 87: 33.14		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		430157 RHG05_HUMAN (500-649): 3.85e-15: 82.8: 30.67		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00