HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: ALMS1 (Q8TCU4)
Centrosome-associated protein ALMS1 (Alstrom syndrome protein 1)
Gene: ALMS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 35941108
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 4168
+	Hs
		1254007 LATS2_HUMAN (13-1121): 0: 751: 49.61		ALMS1_HUMAN (1-4168): 0: 3024: 100.00
+	Hs
		325829 LATS1_HUMAN (1-1130): 0: 934: 100.00		TITIN_HUMAN (3-1424): 2e-23: 113: 8.92
+	Hs
		727323 LATS2_HUMAN (13-1121): 0: 751: 49.61		NU214_HUMAN (1222-2232): 5.74e-12: 74.7: 10.73
+	Hs
		1264826 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		TITIN_HUMAN (3-1424): 2e-23: 113: 8.92
+	Hs
		682094 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		NCOR2_HUMAN (62-1792): 9.19e-12: 74.4: 9.21
+	Hs
		152597 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		KMT2D_HUMAN (1682-2250): 3.94e-11: 72.1: 9.67