HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: TRR (Q8IRW8)
Histone-lysine N-methyltransferase trr (EC 2.1.1.354) (Lysine N-methyltransferase 2C) (Trithorax-related protein)
Gene: TRR

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005700 - polytene chromosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 2431
+	Hs
		355489 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		NSD2_HUMAN (1798-2430): 1.4e-120: 419: 17.49
+	Hs
		355534 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		NSD2_HUMAN (1798-2430): 1.4e-120: 419: 17.49
+	Hs
		998773 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		NSD3_HUMAN (1786-2430): 4.07e-105: 373: 15.37
+	Hs
		998691 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		EHMT2_HUMAN (1761-2427): 1.15e-104: 368: 16.64
+	Hs
		998694 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		NSD1_HUMAN (1804-2430): 1.96e-88: 325: 17.31
+	Hs
		216410 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SUV91_HUMAN (2027-2430): 1.06e-85: 289: 17.93
+	Hs
		998807 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SUV92_HUMAN (2026-2431): 6.43e-84: 284: 16.71
+	Hs
		998359 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		EZH2_HUMAN (1976-2412): 7.81e-80: 283: 15.92
+	Hs
		342152 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		BRD1_HUMAN (1709-2262): 1.89e-77: 282: 14.07
+	Hs
		342201 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		BRD1_HUMAN (1709-2262): 1.89e-77: 282: 14.07
+	Hs
		998846 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		ASH1L_HUMAN (2120-2430): 5.4e-74: 278: 19.39
+	Hs
		998821 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		EHMT1_HUMAN (1702-2427): 1.77e-74: 276: 15.25
+	Hs
		998948 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SET1B_HUMAN (2153-2431): 6e-68: 257: 27.63
+	Hs
		175872 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SET1A_HUMAN (2156-2431): 1.3e-65: 250: 26.94
+	Hs
		998772 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SETD2_HUMAN (2240-2430): 1.56e-65: 250: 28.08
+	Hs
		998234 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KMT2A_HUMAN (1892-2224): 5.03e-61: 235: 26.35
+	Hs
		1041540 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		KMT2A_HUMAN (1892-2224): 5.03e-61: 235: 26.35
+	Hs
		998942 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KMT2B_HUMAN (1857-2120): 2.34e-51: 203: 29.06
+	Hs
		998565 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KMT2C_HUMAN (925-1356): 1.66e-09: 66: 9.82
+	Hs
		161446 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KMT2D_HUMAN (37-1354): 7.23e-09: 64.1: 10.28