HitPredict

Interactor 1: CLCA (P09496)
Clathrin light chain A (Lca)
Gene: CLTA

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030132 - clathrin coat of coated pit GO:0048268 - clathrin coat assembly
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 896
+	Hs
		451645 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		451583 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40
+	Hs
		451450 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Hs
		451463 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		FKB15_HUMAN (76-873): 1.31e-37: 154: 11.35
+	Hs
		451745 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40
+	Hs
		451587 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98
+	Hs
		451680 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Ce
		954169 P90961_CAEEL (30-244): 4.57e-32: 118: 24.31		Q9U2T9_CAEEL (5-425): 1.07e-23: 109: 11.85