HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RNF38 (Q9H0F5)
E3 ubiquitin-protein ligase RNF38 (EC 2.3.2.27) (RING finger protein 38) (RING-type E3 ubiquitin transferase RNF38)
Gene: RNF38

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	25801170
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 515
+	Hs
		475941 UBC_HUMAN (1-685): 0: 846: 100.00		RN111_HUMAN (2-508): 6.5e-50: 186: 17.74
+	Hs
		476301 UBC_HUMAN (1-685): 0: 846: 100.00		RN126_HUMAN (253-514): 1e-42: 156: 19.29
+	Hs
		476628 UBC_HUMAN (1-685): 0: 846: 100.00		RN115_HUMAN (260-515): 7.52e-39: 145: 17.36
+	Hs
		476458 UBC_HUMAN (1-685): 0: 846: 100.00		RNF12_HUMAN (13-508): 1.16e-32: 133: 16.41
+	Hs
		475946 UBC_HUMAN (1-685): 0: 846: 100.00		ARK2C_HUMAN (158-510): 4e-31: 125: 19.95
+	Hs
		476063 UBC_HUMAN (1-685): 0: 846: 100.00		ZNRF1_HUMAN (290-501): 1.92e-31: 122: 15.25
+	At
		1091813 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RNG1L_ARATH (312-515): 1.71e-34: 134: 20.09
+	At
		955780 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		ATL1_ARATH (436-508): 7.18e-28: 116: 33.33
+	Mm
		476971 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN111_MOUSE (2-508): 6.61e-50: 186: 18.31
+	Mm
		476994 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN115_MOUSE (260-515): 1.65e-41: 152: 17.36
+	Mm
		476947 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN126_MOUSE (253-514): 1.39e-40: 150: 18.09
+	Hs
		475173 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RN126_HUMAN (253-514): 1e-42: 156: 19.29
+	Mm
		477051 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RNF12_MOUSE (65-510): 1.69e-33: 136: 15.22
+	Hs
		398150 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		RN115_HUMAN (260-515): 7.52e-39: 145: 17.36
+	Hs
		475109 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		ZNRF1_HUMAN (290-501): 1.92e-31: 122: 15.25
+	Zm
		79051 B6SKC9_MAIZE (514-679): 1.23e-22: 104: 25.88		C0P544_MAIZE (369-507): 5.32e-30: 118: 23.40