Interactor 1: LYN (P25911)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: P85A (P26450)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: Pik3r1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 8395016
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, PI3K_P85_iSH2~SH2, SH2~SH3_1
Common GO terms GO:0005102 - signaling receptor binding
GO:0005161 - platelet-derived growth factor receptor binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 512
Mm

1 724
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+ Gg
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024