HitPredict

Interactor 1: PRS6A (P33297)
26S proteasome regulatory subunit 6A (Tat-binding protein homolog 1) (TBP-1)
Gene: RPT5

Interactor 2: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 16284124, 10873636, 9741626, 9584156, 16554755, 16429126, 18467557, 19446323, 37968396, 21658604, 22237024, 22615397, 21139140, 22940862
Identification Methods affinity chromatography technology, biochemical, protein complementation assay, pull down, dihydrofolate reductase reconstruction, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~RPN1_C, AAA_lid_3~RPN1_RPN2_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008540 - proteasome regulatory particle, base subcomplex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 434
Sc

1 993
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Last updated: 15 Jul 2024