HitPredict

Interactor 1: TOR1 (P35169)
Serine/threonine-protein kinase TOR1 (EC 2.7.11.1) (Dominant rapamycin resistance protein 1) (Phosphatidylinositol kinase homolog TOR1) (Target of rapamycin kinase 1)
Gene: TOR1

Interactor 2: RUVB2 (Q12464)
RuvB-like protein 2 (RUVBL2) (EC 3.6.4.12) (TIP49-homology protein 2) (TIP49b homolog)
Gene: RVB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2470 Sc			1 471
+	Hs
		787605 MTOR_HUMAN (72-2470): 0: 1605: 38.29		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		787606 MTOR_HUMAN (72-2470): 0: 1605: 38.29		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Dm
		1358868 TOR_DROME (14-2470): 0: 1545: 36.55		RUVB2_DROME (3-471): 0: 675: 62.34
+	Dm
		1366582 TOR_DROME (14-2470): 0: 1545: 36.55		RUVB1_DROME (10-448): 0: 622: 40.18
+	Hs
		1038195 ATR_HUMAN (292-2469): 0: 917: 16.27		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Hs
		1031646 ATM_HUMAN (585-2469): 0: 859: 16.36		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Mm
		888083 TRRAP_MOUSE (427-2469): 0: 825: 13.69		RUVB1_MOUSE (10-448): 0: 658: 41.72
+	Sp
		294006 TRA1_SCHPO (60-2469): 0: 774: 13.10		RUVB2_SCHPO (1-471): 0: 679: 67.52
+	Hs
		944485 PRKDC_HUMAN (481-2469): 0: 757: 14.21		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Dm
		1211950 TRA1_DROME (323-2469): 0: 802: 13.14		RUVB1_DROME (10-448): 0: 622: 40.18
+	Hs
		944486 PRKDC_HUMAN (481-2469): 0: 757: 14.21		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Sp
		1319465 TRA1_SCHPO (60-2469): 0: 774: 13.10		RUVB1_SCHPO (9-444): 0: 631: 40.22
+	Sc
		744182 ATR_YEAST (831-2470): 1.45e-173: 595: 15.64		RUVB2_YEAST (1-471): 0: 707: 100.00
+	Sc
		755452 TRA1_YEAST (29-2470): 0: 668: 12.66		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Sc
		744167 ATR_YEAST (831-2470): 1.45e-173: 595: 15.64		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Hs
		1300093 SMG1_HUMAN (2367-2469): 8.53e-17: 90: 24.27		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		1300094 SMG1_HUMAN (2367-2469): 8.53e-17: 90: 24.27		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Hs
		1376985 TRRAP_HUMAN (228-1290): 1.52e-09: 66.2: 9.44		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		1377044 TRRAP_HUMAN (228-1290): 1.52e-09: 66.2: 9.44		RUVB1_HUMAN (10-448): 0: 658: 41.72