HitPredict

Interactor 1: B1AT92 (B1AT92)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: Grb2

Interactor 2: GAB2 (Q9Z1S8)
GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (PH domain-containing adaptor molecule p97)
Gene: GAB2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	20697350
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 203 Mm			1 665
+	Mm
		1221267 GRB2_MOUSE (1-203): 1.49e-65: 202: 90.32		GAB2_MOUSE (1-665): 1.63e-175: 517: 100.00
+	Mm
		1191823 GRB2_MOUSE (1-203): 1.49e-65: 202: 90.32		Q3ZB59_MOUSE (1-665): 4.46e-175: 515: 99.85
+	Hs
		988039 GRB2_HUMAN (1-203): 1.52e-65: 202: 90.32		GAB2_HUMAN (4-665): 8.8e-173: 510: 90.67
+	Mm
		683116 LYN_MOUSE (3-188): 4.62e-41: 147: 28.08		GAB2_MOUSE (1-665): 1.63e-175: 517: 100.00
+	Hs
		987613 GRB2_HUMAN (1-203): 1.52e-65: 202: 90.32		GAB1_HUMAN (5-664): 1.33e-121: 379: 35.81
+	Mm
		1221262 GRB2_MOUSE (1-203): 1.49e-65: 202: 90.32		GAB1_MOUSE (5-664): 4.06e-120: 375: 36.23
+	Hs
		463507 LYN_HUMAN (3-188): 1.07e-40: 146: 28.57		GAB1_HUMAN (5-664): 1.33e-121: 379: 35.81
+	Hs
		987801 GRB2_HUMAN (1-203): 1.52e-65: 202: 90.32		GAB3_HUMAN (5-656): 4.26e-91: 296: 31.22
+	Hs
		362328 ABL1_HUMAN (4-151): 1.41e-50: 177: 32.68		GAB3_HUMAN (5-656): 4.26e-91: 296: 31.22
+	Hs
		440651 FYN_HUMAN (4-188): 1.09e-40: 146: 27.54		GAB3_HUMAN (5-656): 4.26e-91: 296: 31.22
+	Hs
		463682 LYN_HUMAN (3-188): 1.07e-40: 146: 28.57		GAB3_HUMAN (5-656): 4.26e-91: 296: 31.22
+	Hs
		215914 GRB2_HUMAN (1-203): 1.52e-65: 202: 90.32		SYNJ1_HUMAN (123-640): 1.36e-51: 195: 14.80
+	Hs
		987707 GRB2_HUMAN (1-203): 1.52e-65: 202: 90.32		PKHA7_HUMAN (1-608): 3.67e-49: 187: 13.06
+	Hs
		987954 GRB2_HUMAN (1-203): 1.52e-65: 202: 90.32		PKHA2_HUMAN (3-227): 4.14e-44: 165: 21.83
+	Hs
		987694 GRB2_HUMAN (1-203): 1.52e-65: 202: 90.32		PKHS1_HUMAN (8-314): 4.25e-43: 163: 17.70
+	Ce
		111780 SEM5_CAEEL (1-202): 3.44e-60: 189: 54.67		SOC1_CAEEL (3-404): 1.92e-47: 175: 12.83
+	Dm
		1061478 GRAP_DROME (1-201): 6.6e-56: 178: 60.38		DOS_DROME (7-464): 2.16e-41: 163: 20.16
+	Hs
		463588 LYN_HUMAN (3-188): 1.07e-40: 146: 28.57		PKHA7_HUMAN (1-608): 3.67e-49: 187: 13.06
+	Hs
		319045 LYN_HUMAN (3-188): 1.07e-40: 146: 28.57		K0754_HUMAN (99-647): 1.51e-39: 159: 10.58
+	Hs
		987772 GRB2_HUMAN (1-203): 1.52e-65: 202: 90.32		SESQ1_HUMAN (8-117): 3.48e-13: 72: 27.43