HitPredict

Interactor 1: GNAI1 (B2RSH2)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (EC 3.6.5.-) (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Interactor 2: PI2R (P43252)
Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)
Gene: Ptgir

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11443126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~G-alpha
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Mm			1 415
+	Hs
		418593 GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89		TA2R_HUMAN (44-352): 2.28e-86: 268: 31.27
+	Hs
		458371 GNAI1_HUMAN (1-354): 0: 516: 100.00		ADRB2_HUMAN (21-360): 4.32e-69: 226: 14.96
+	Hs
		640498 GNAQ_HUMAN (1-353): 3.05e-167: 472: 52.26		TA2R_HUMAN (44-352): 2.28e-86: 268: 31.27
+	Hs
		458244 GNAI3_HUMAN (1-354): 0: 507: 93.79		ADRB2_HUMAN (21-360): 4.32e-69: 226: 14.96
+	Hs
		989839 GNAI1_HUMAN (1-354): 0: 516: 100.00		MTR1L_HUMAN (28-411): 8.51e-64: 217: 13.10
+	Hs
		418567 GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89		ADRB2_HUMAN (21-360): 4.32e-69: 226: 14.96
+	Hs
		640491 GNA11_HUMAN (1-353): 1.37e-162: 460: 51.13		TA2R_HUMAN (44-352): 2.28e-86: 268: 31.27
+	Hs
		880902 GNAI1_HUMAN (1-354): 0: 516: 100.00		MTR1B_HUMAN (2-363): 6.24e-62: 205: 19.46
+	Mm
		636979 GNA11_MOUSE (1-353): 7.61e-164: 463: 50.85		PI2R_MOUSE (1-415): 3.17e-81: 257: 100.00
+	Hs
		475919 GNAI3_HUMAN (1-354): 0: 507: 93.79		MTR1B_HUMAN (2-363): 6.24e-62: 205: 19.46
+	Hs
		458271 GNAT2_HUMAN (1-354): 3.22e-172: 484: 69.49		ADRB2_HUMAN (21-360): 4.32e-69: 226: 14.96
+	Hs
		640512 GNA13_HUMAN (2-353): 2.27e-155: 442: 39.17		TA2R_HUMAN (44-352): 2.28e-86: 268: 31.27
+	Hs
		418612 GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89		OPRD_HUMAN (4-364): 4.23e-62: 206: 13.86
+	Hs
		418621 GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89		MTR1B_HUMAN (2-363): 6.24e-62: 205: 19.46
+	Hs
		482579 GNAO_HUMAN (1-354): 1.39e-175: 493: 72.11		OPRM_HUMAN (6-382): 2.83e-62: 207: 13.58
+	Hs
		482584 GNAO_HUMAN (1-354): 1.39e-175: 493: 72.11		OPRD_HUMAN (4-364): 4.23e-62: 206: 13.86
+	Hs
		845501 GNAQ_HUMAN (1-353): 3.05e-167: 472: 52.26		PI2R_HUMAN (29-415): 8.34e-69: 224: 78.87
+	Bt
		388110 GNAT1_BOVIN (1-354): 4.13e-169: 476: 67.80		OPSD_BOVIN (4-361): 1.06e-61: 204: 15.98
+	Rn
		475873 GNAI3_RAT (1-354): 4.32e-180: 504: 93.50		AA3R_RAT (53-320): 8.08e-15: 76.6: 18.52
+	Rn
		418562 GNAI2_RAT (1-354): 7.55e-179: 501: 88.17		AA3R_RAT (53-320): 8.08e-15: 76.6: 18.52