Interactor 1: IRS1 (P35569)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1
Interactor 2: CRK (Q64010)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9729467 |
| Identification Methods | far western blotting |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_1 |
| Common GO terms | GO:0005159 - insulin-like growth factor receptor binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0042169 - SH2 domain binding |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
