Interactor 1: MLH1 (P40692)
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
Gene: MLH1
Interactor 2: PMS1 (P54277)
PMS1 protein homolog 1 (DNA mismatch repair protein PMS1)
Gene: PMS1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.969 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11292842, 17148452, 26496610, 33961781, 34591612, 36652389, 10748159, 25502805 |
| Identification Methods | two hybrid, affinity chromatography technology, cross-linking study, lexa vp16 complementation, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_mis_repair~HATPase_c_3, HATPase_c_3~HATPase_c_3 |
| Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006298 - mismatch repair GO:0016887 - ATP hydrolysis activity GO:0019899 - enzyme binding and 2 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
