HitPredict

Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 35271311, 9845365, 21300803, 22573825, 15985610
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~HSA, Actin~SNF2-rel_dom
Common GO terms GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005634 - nucleus
and 25 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1647
Hs

1 375
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024