Interactor 1: LEPR (P48356)
Leptin receptor (LEP-R) (B219) (OB receptor) (OB-R) (CD antigen CD295)
Gene: LEPR
Interactor 2: JAK2 (Q62120)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21264353 |
| Identification Methods | anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~fn3 |
| Common GO terms | GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0120162 - positive regulation of cold-induced thermogenesis |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
